Jennifer Kang-Mieler (jkangmie)

Jennifer Kang-Mieler

Professor and Chair of the Department of Biomedical Engineering

Charles V. Schaefer, Jr. School of Engineering and Science

Department of Biomedical Engineering

McLean Hall 108B
(201) 216-3557

Research

Ocular drug delivery systems, Retinal imaging, Biomarkers, Retinal hemodynamics and electrophysiology

General Information

Dr. Kang-Mieler’s translational NIH-supported research projects include ocular drug delivery, retinal imaging and biomarkers, retinal blood flow, and electrophysiology. Her clinical interests include retinal vascular diseases such as age-related macular degeneration and diabetic retinopathy.

Experience

Education:
Northwestern University, Evanston IL
B.A. in Mathematics
M.S. in Applied Mathematics
Ph.D. in Biomedical Engineering

University of Illinois at Chicago, Chicago, IL
Post-doctoral research, Department of Ophthalmology and Visual Sciences

Institutional Service

  • Master's Curriculum Committee Member
  • New BME staff hire Chair
  • Center for Health Innovation (CHI) Chair
  • Faculty Search Chair
  • Animal Care Facility renovation committee Member
  • BME newsletter and social media promotion Chair
  • PhD Curriculum Committee Member
  • UG Curriculum Committee Member
  • Faculty nomination Chair
  • SES Strategic Planning Committee Chair
  • Reappointment and promotion Chair

Professional Service

  • NIH Brain Imaging, Vision, Bioengineering and Low Vision Technology Development (BIVT)
  • VentureWell and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) DEBUT Undergraduate Biomedical Design and Innovation Competition Judge
  • Northeast Bioengineering Conference Conference Chair
  • BMES Council of Chairs Education Summit Conference co-chair
  • BMES BME Council of Chairs
  • Propelify Innovation Festival BetterWellness Challenge Judge

Honors and Awards

Walter P. Murphy Fellowship, Graduate Fellowship, Northwestern University

General Electric Faculty of the Future Intern Fellowship, General Electric and McCormick School of Engineering and Applied Science, Northwestern University

Nelson Fellowship Award, Nelson Foundation and the Department of Ophthalmology & Visual Sciences, University of Illinois at Chicago

Whitaker Foundation Fellow

Fellow of Association for Research in Vision and Ophthalmology (FARVO-Silver)

Pan-American Association of Ophthalmology (PAAO) and Retina Research Foundation (RRF) Paul Kayser Global Award

Asia-Pacific Academy of Ophthalmology (APAO) Achievement Award

Fellow of Association for Research in Vision and Ophthalmology (FARVO-Gold)

Club Jules Gonin and Retina Research Foundation Award

Professional Societies

  • AIMBE – American Institute for Medical and Biological Engineering (AIMBE) Fellow
  • Club Jules Gonin Member
  • International Retinal Imaging Society Member
  • PAAO – Pan-American Association of Ophthalmology (PAAO) Member
  • Dowling Society Member
  • SWE – Society for Women Engineers (SWE) Member
  • Macula Society Member
  • Retina Society Member
  • Association for Ocular Pharmacology and Therapeutics Member
  • International Society on Oxygen Transport to Tissue Member
  • ASEE – American Society for Engineering Education (ASEE) Member
  • ISCEV – International Society for Clinical Electrophysiology of Vision (ISCEV) Member
  • ARVO – Association for Research in Vision and Ophthalmology (ARVO) Fellow
  • BMES – Biomedical Engineering Society (BMES) Member
  • ASRS – American Society of Retina Specialists (ASRS) Member

Grants, Contracts and Funds

Principal Investigator: National Institute of Health (R01) (R01 EY029298). “Sustained Ocular Drug Delivery System for Anti-VEGF Agents”

Principal Investigator: National Institute of Health (R01) (R01 EY032222) “Dynamic Tracer Kinetic Model to Detect Preclinical Diabetic Retinopathy (DR)”

Co-Investigator: Center for Equine Health Research Grant, University of California, Davis “Pharmacokinetics and biocompatibility of a novel cyclosporine-loaded microsphere thermo-responsive hydrogel drug delivery system in horses”

Patents and Inventions

Biodegradable microsphere-hydrogel ocular drug delivery system (Patent No 10,980,882)

Biodegradable extended release microsphere-hydrogel ocular drug delivery system and method (Patent No 11,266,608)

Selected Publications

Conference Proceeding

  1. Vavrek, S.; Kayaalp-Nalbant, E.; Konopek, N.; Bou-Ghanem, G.; Fawzi, A.; Mieler, W.; Kang-Mieler, J.; Tichauer, K. (2023). Fluorescein videoangiography data analysis protocol for mapping retinal vascular permeability in humans. Proc SPIE (vol. 12360:123600L.).
  2. Kayaalp-Nalbant, E.; Annepureddy, L.; Hu, S.; Liu, W.; Tang, F.; Sun, Z.; Chung, C.; Mieler, W.; Kang-Mieler, J.; Tichauer, K. (2022). Optimizing the protocol for retinal vascular permeability mapping from fluorescein video angiography data. Proc SPIE (vol. 11941:119410K).

Journal Article

  1. Ham, Y.; Mehta, H.; Kang-Mieler, J.; Mieler, W.; Chang, A. (2023). Novel drug delivery methods and approaches for the treatment of retinal diseases.. Asia Pac J Ophthalmol (4 ed., vol. 12, pp. 402-413).
  2. Yuan, B.; Rudeen, K.; Li, J.; Williams, B.; Sumughan, S.; Lopez, G.; An, H.; Kang-Mieler, J.; Chee, A. (2023). Biodegradable microspheres and hydrogel drug delivery system of tumor necrosis factor (TNF) inhibitor and growth differentiation factor 5 (GDF5) reduced disc inflammation in the rabbit model.. Spine (15 ed., vol. 48, pp. E257-E265).
  3. Rudeen, K. M.; Liu, W.; Mieler, W. F.; Kang-Mieler, J. J. (2022). Simultaneous Release of Aflibercept and Dexamethasone from an Ocular Drug Delivery System. . Current Eye Research (7 ed., vol. 47, pp. 1034-1042).