Molecular Modeling and Treatment of Disease
Professor Tolias leads translational multidisciplinary research efforts in personalized medicine, focused on patient specific genomic analysis of disease and subsequent selection of therapeutic options based on the unique genetic make-up of an individual. Therapy is then assessed in an ex vivo model developed from the patient's own biopsies grown in 3D microfluidic perfusion culture.
Clinical diagnostics, drug development, therapeutic selection and assessment, device engineering
Molecular-, cellular-, developmental-, and computational-biology, microbiology, immunology, genetics, genomics, proteomics, tissue engineering.