2014 Symposium on Innovation in Healthcare Technology and Delivery
Monday March 10, 2014,
Stevens Institute of Technology
Babbio Center, Hoboken NJ 07030
Hosted by the Stevens Center for Healthcare Innovation
Moderated by Professor Peter Tolias, Ph.D.
The 2014 Symposium on Innovation in Healthcare Technology and Delivery, hosted by the Center for Healthcare Innovation at the Stevens Institute of Technology, highlighted multidisciplinary advances in medical technology, work force development and healthcare delivery in the era of the Affordable Care Act. This half-day affair was held on university grounds and featured two sessions, each of which included keynote lectures, short presentations by select faculty and external collaborators and panel discussions. The session entitled "New Models for Drug Development and Personalized Therapy" highlighted advances using cancer biopsies as personalized models for preclinical and clinical drug development and therapy selection. It also discussed how new academic innovation centers are driving drug discovery and concluded with the effects of plasma proteins on lung injury. The second session entitled "Healthcare Delivery in the Era of the Affordable Care Act" underscored challenges facing healthcare providers in delivering affordable healthcare with examples of business models, workforce development and technologies that facilitate the process. An audience from the Northeast attended that included administrators from hospitals, clinics, accountable care organizations and health insurance providers as well as investigators from research universities and R&D scientists and executives from pharmaceutical, biotechnology and medical device companies.
1:00-1:30: Opening Remarks
Nariman Farvardin, Ph.D., Professor and University President, Stevens Institute of Technology
George Korfiatis, Ph.D., McLean Chair Professor, Provost and University Vice President, Stevens Institute of Technology
Mo Dehghani, Ph.D., Industry Professor and Vice Provost of Research, Stevens Institute of Technology
Peter Tolias, Ph.D., Professor and Director of the Center for Healthcare Innovation, Stevens Institute of Technology
Peter Tolias Presentation
1:30-3:15 New Models for Drug Development and Personalized Therapy
Highlighted advances in developing new models for preclinical and clinical drug development as well as therapy selection.
Keynote Lecture: Cell Reprograming and Applications to Targeted Therapies
Richard Schlegel, MD, Ph.D., Professor and Chairman of the Department of Pathology, Director of the Center for Cellular Reprogramming, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center
Richard Schlegel Presentation
Microphysiological Human Tissue Reconstruction
Woo Lee, Ph.D., George Meade Bond Professor, Stevens Institute of Technology
Personalized Therapeutics for the Treatment of Hematological Malignancies
Jenny Zilberberg, Ph.D., Researcher, Hackensack University Medical Center
Jenny Zilberberg Presentation
Enabling Drug Discovery in Academia
Alvin Stern, Ph.D., Visiting Professor and Director of the Biotechnology and Drug Discovery Laboratory at the CHI in Stevens
Plasma protein effects on alveolar surface tension in lung injury
Carrie Perlman Ph.D., Assistant Professor, Stevens Institute of Technology
3:30-5:15 Healthcare Delivery in the Era of the Affordable Care Act
Underscored challenges facing healthcare providers in delivering affordable healthcare with examples of business models, workforce development and technologies that facilitate the process.
Keynote Lecture: Healthcare Delivery in the Era of the Affordable Care Act
William Rouse, Ph.D., Alexander Crombie Humphreys Professor and Director of the Center for Complex Systems & Enterprises, Stevens Institute of Technology
William Rouse Presentation
Healthcare delivery - now vs. the future
Mark Spektor, DO, President and CEO, Bayonne Medical Center, CarePoint Health
Mobile Phone Enabled Social Community: Extraction for Controlling DiseasePropagation in Healthcare
Yingying Chen, Ph.D., Associate Professor, Stevens Institute of Technology
Yingying Chen Presentation
Causal Inference from Uncertain Data
Samantha Kleinberg, Ph.D., Assistant Professor, Stevens Institute of Technology
Samantha Kleinberg Presentation
Practical Leadership Strategies for The Real-World of Community Healthcare
Donald Lombardi, Ph.D., Industry Associate Professor, Stevens Institute of Technology
Donald Lombardi Presentation
Dr. Richard Schlegel received his M.D. and Ph.D. degrees from Northwestern University Medical School, and was a resident and post-doctoral fellow at Harvard Medical School (Brigham Hospital) in the fields of Pathology and Virology. Beginning in 1980, Dr. Schlegel was an investigator, then a senior investigator at the National Cancer Institute (NCI), and later served as chief of the Cell Regulation and Transformation Section in the Laboratory of Tumor Virus Biology at NCI. In 1990, he joined Georgetown University Medical Center as an associate professor in the Department of Pathology, and became department chair in 2003. Dr. Schlegel’s laboratory at Georgetown University developed the human papillomavirus (HPV) vaccine, which was awarded the dominant patent for the vaccine technology from the U.S. Patent Office in 2005, and in June 2006 received approval from the U.S. Food and Drug Administration to use the HPV vaccine in humans. HPV causes almost all incidences of cervical cancer, the second-leading cause of cancer deaths in women worldwide. Based on his work elucidating the mechanism by which HPV causes cancer, Dr. Schlegel has applied the knowledge gained to the field of regenerative medicine and developed a breakthrough technology that enables the conditional reprogramming and growth of primary human cells of epithelial origin in culture. This technology is being applied to drug development and personalized medicine, as cancer biopsies can be grown in the lab to assess which drugs will be most beneficial for a particular patient.
Dr. William B. Rouse received his B.S. from the University of Rhode Island, and his S.M. and Ph.D. from the Massachusetts Institute of Technology. He is currently the Alexander Crombie Humphreys Chair in Economics of Engineering in the School of Systems and Enterprises, Director of the Center for Complex Systems and Enterprises at Stevens Institute of Technology and Professor Emeritus in the School of Industrial and Systems Engineering at the Georgia Institute of Technology. His previous positions at Georgia Institute of Technology include Executive Director of the university- Tennenbaum Institute and Chair of the School of Industrial and Systems Engineering. Dr. Rouse was also the CEO of two innovative software companies – Enterprise Support Systems and Search Technology – and held faculty positions at Georgia Tech, University of Illinois, Delft University of Technology, and Tufts University. His expertise includes individual and organizational decision-making and problem solving, as well as design of organizations and information systems. In these areas, he has consulted with well over one hundred large and small enterprises in the private, public, and non-profit sectors, where he has worked with several thousand executives and senior managers. His current research focuses on understanding and managing complex public-private systems, such as healthcare, energy and defense, with emphasis on mathematical and computational modeling of these systems for the purpose of policy design and analysis. Dr. Rouse has been designated a lifetime National Associate of the National Research Council and National Academies.