By Girish Agarwal
The Texas A & M University
It is well known that the diffraction of light limits the resolution achievable in microscopy. The diffraction barrier to resolution, for example, limits the transverse resolution to about lambda/2. This limit started to be overcome in early nineties by Hell who introduced ideas from quantum mechanics and shaped fields. I will review the newer developments based on the anti-bunching property of quantum emitters and the strategies based on quantum optical correlations of increasing order, that yield a spatial resolution reaching far into the sub-diffraction regime. Further I will discuss how strong squeezing and entangled photon pairs enable two photon microscopy at much lower powers which is especially useful for biological systems. Data on important biomarkers will be presented.
Girish Agarwal is an authority in quantum optics and is the author of “Quantum Optics” published by the Cambridge University Press. His work has been recognized by a large number of awards, including the Max-Born Prize from the Optical Society of America in 1988, the physics prize of the World Academy of Sciences , the Humboldt Research Award (1997) of Germany. He was elected fellow of several societies-The Royal Society (UK), American Physical Society; Optical Society of America, He received The Eminent Faculty Award of the Oklahoma State University where he was Noble Foundation Chair and regent’s professor. He is currently developing experimental program in microscopy and quantum sensing at The Texas A & M University.