Particle kinematics and kinetics, systems of particles, work-energy, impulse and momentum, rigid-body kinematics, relative motion, Coriolis acceleration, rigid-body kinetics, direct and oblique impact, eccentric impact.
Concepts of energy, heat and work; thermodynamic properties of substances and property relationships, phase change; First and Second Laws for closed and open systems including steady and transient processes and cycles; using entropy; representative applications including vapor and gas power and refrigeration cycles.
This course is intended to teach modern systematic design techniques used in the practice of mechanical engineering. Methodology for the development of design objective(s), literature surveys, base case designs, and design alternatives are given. Economic analyses with an emphasis on capital investment and operating costs are introduced. Integrated product and process design concepts are emphasized with case studies. Students are encouraged to select their senior capstone design project near the end of the course, form teams, and commence preliminary work. A number of design projects are required of all students.
Applications of First and Second Laws to thermal systems including gas turbine, and internal and external combustion engines. Vapor cycles, including supercritical binary and combined cycles, regeneration and recuperation, gas compression, refrigeration and gas liquefaction. Analysis of thermal processes, including available energy and availability, irreversibility, effectiveness. Laboratory work in air compressors, internal combustion engines, furnaces, heat pumps, and gas turbines.
Properties of a fluid, basic flow analysis techniques, fluid kinematics, hydrostatics, manometry, pressure distribution in rigid body motion of a fluid, control volume analysis, conservation of mass, linear and angular momentum, Bernoulli and energy equations, dimensional analysis, viscous flow in pipes, flow metering devices, external flows, estimation of lift and drag, turbo-machinery, open channel flow.
Modeling and simulation methodologies including model-block building, logical and data modeling, validation, simulation and trade-off analysis, decision-making, and optimization. Product and assembly modeling; visual simulation; process modeling; production modeling; process plans and resource modeling, entity flow modeling including conveyors, transporters, and guided vehicles; Input and output statistical analysis. Several CAD/CAE simulation software are used.
The principles of dynamics as applied to the analysis of the accelerations and dynamic forces in machines such as linkages, cam systems, gears trains, belts, chains and couplings. The effect these dynamic forces have on the dynamic balance and operation of the machines and the attending stresses in the individual components of the machines. Some synthesis techniques. Students also work in teams on a semester long project associated with the design of a mechanical system from recognizing the need through a detailed conceptual design.
Application of the principles of strength of materials to the analysis and design of machine parts. Stress and deflection analysis. Curved bars, multi-support shafts, torsion, cylinders under pressure, thermal stresses, creep, and relaxation, rotating disks, fasteners, springs, bearings, gears, brakes and other machine elements are considered. Failure of structural materials under cyclic stress.
Technology and economics of energy sources, storage and utilization, overview of fundamental concepts of mechanical, thermal, chemical, nuclear, electrical energy conversion (practical and visionary), thermo chemical conversion, including combustion in power plants, propulsion systems, thermo mechanical conversion in nozzles and turbomachinery, "direct" energy conversion in fuel cells, etc., nuclear energy conversion.
Individual investigation of a substantive character undertaken at an undergraduate level under the guidance of a faculty advisor leading to a thesis with a public defense. Thesis comitee will consist of the faculty advisor and one or more reader.
Individual investigation of a substantive character undertaken at an undergraduate level under the guidance of a faculty advisor leading to a thesis with a public defense. Thesis comitee will consist of the faculty advisor and one or more reader.
Experiments in selected mechanical engineering systems areas, including principles and applications of experimentation, data-acquisition, design of experiments, and written and oral reporting on experimental hardware and results.
Multidimensional stress, strain and transformation equations, yield conditions and theories of failure, constitutive laws including linear elasticity, viscoelasticity and temperature influences, equations of elasticity, simple applications to uniaxial stress and symmetric bending, unsymmetrical bending and shear center of beams, torsions, combined stresses with applications to beams, thin-walled cylinders and pressure tanks, shrink fits, bending beyond the elastic limit, instability and energy methods.
Static and dynamic force analysis of mechanisms, dynamics of reciprocating and rotating machinery, balancing of machinery, friction and wear, vibration and noise control in machines, manipulators and robots, computer-aided design.
Analysis and synthesis of feedback control systems to achieve specified stability and performance criteria, stability via root-locus techniques, Nyquist's criterion, Bode and Nichol's plots, effect of various control laws and pole-zero compensation on performance, applications to servomechanisms, hydraulic and pneumatic control systems, analysis of nonlinear systems.
Analysis of both bulk-forming (forging, extrusion, rolling, etc.) and sheet-forming processes, metal cutting, and other related manufacturing processes; physics and stochastic nature of manufacturing processes and their effects on quality, rate, cost and flexibility; role of computer-aided manufacturing in manufacturing system automation; methodologies used to plan and control a manufacturing system, forecasting, production scheduling, facility layout, inventory control, and project planning.
Analysis of thermodynamics, hydraulic, environmental, and economic considerations that affect the design and performance of modern power plants; overview of power generation system and its components, including boilers, turbines, circulating water systems, and condensate-feedwater systems; fuels and combustion; auxiliary pumping and cleanup systems; gas turbine and combined cycles; and introduction to nuclear power plants and alternate energy systems based on geothermal, solar, wind, and ocean energy.
A development of the background necessary for nuclear engineering, beginning with a review of atomic physics and including radioactivity, nuclear reactions, neutron physics and elementary reactor theory, reactor dynamics and control, reactor types.
Analysis of the automotive vehicle as an entire integrated system under highway and off-road conditions. Significant subject areas include power-train design, control and stability; suspension design, tire-road interface, soil-vehicle interface, four-wheeled, tracked and unconventional vehicles; emphasis is on design theory.
This course covers fundamental principles related to nuclear power reactor reliability, safety and waste disposal. Topics include radiation and radiological concepts and measurement, the fuel cycle and waste classification, State and Federal regulations and regulatory agencies, radiochemistry and the environmental fate of radionuclides, uranium-related wastes, low-level waste characteristics and management, high-level wastes characteristics and management, private fuel storage, waste package stability, risk assessment, geologic repositories, theory of retrievability in waste management, deep-well injection, transporting radioactive wastes, decontamination and decommission, transmutation, an international perspective on radioactive waste management, the Global Nuclear Energy Partnership, and the latest from the Blue Ribbon Commission.
This course covers design methodologies for major systems and components in a nuclear power plant and discusses how the integrated nuclear plant works and the challenges an operator faces. The course provides a study of the interrelationship and propagation of effects that systems and design changes have on one another, especially in relation to nuclear power plant operations and safety. Emphasis is placed on how operations of and faults in systems and components can influence reactivity and core behavior. The students will examine a typical nuclear power plant and those components and systems of the nuclear plant system that have the potential for affecting core power and whose failure could be an initiating event for a plant transient. One main outcome is the ability to predict behavior under complex interactions among systems and to predict transient behavior of the integrated nuclear plant considering factors that are important for safe and efficient operation of the plant including reactivity management and control, coolant inventory control and core heat removal. A replica simulator (PCTRAN) is used as an effective way for students to understand accident control, emergency operating procedures and plant control. The course includes case studies and design projects.
Composite material characterization; composite mechanics of plates, panels, beams, columns, and rods integrated with design procedures; analysis and design of composite structures, joining methods and procedures, introduction to manufacturing processes of filament winding, braiding, injection, compression and resin transfer molding, machining and drilling, and industrial applications.
This course will introduce principles and applications of Nondestructive Evaluation (NDE) techniques which are important in design, manufacturing, and maintenance. Most commonly used methods such as ultrasonics, magnetics, radiography, penetrants, and eddy currents will be discussed. Physical concepts behind each of these methods as well as practical examples of their applications will be emphasized.
This course introduces principles of mechatronics to integrate mechanical, electronic/electrical, and control/computer/software components for motion control systems. Electromechanical components and integration concepts include: machine construction and control concepts, control modes (open/closed loop, servo, and process control) and motion profiles, motion drivers and actuators (AC drives, motors, gearing, servo and stepper motors), PLC control and programming (ladder and Boolean and combinatorial logic interfaces), microprocessor/computer based (logic, operating systems, SCADA, and HMI), field devices, signal conditioning, and communication (I/O hardware and management, vision systems, protocols, and programming languages), and introduction to system integration.Course includes hands-on lab work, small design projects, case studies, and industry guest lectures.
This course introduces the fundamental principles of mechanics applied to the study of biological systems and relates the design of implants and prosthetics to the biomechanics of the musculoskeletal system. Specific types of tissue covered include bone, ligament, skeletal and cardiac muscle, and articular cartilage. An introduction to the basic concepts of continuum mechanics is provided, including finite-deformation kinematics, stress, constitutive equations, and the governing conservation laws of mass, momentum, and energy applied to deformable continua. Rigid-body kinematics is introduced in the context of applications in biomechanics.
This course introduces the basic anatomy of skeletal muscles, tendons, ligaments and joints (including shoulder, hip, knee, foot and ankle). Mechanical principles are applied to the analysis of human movement in daily living, work settings, sports and exercise. Quantitative video analysis techniques are introduced and applied to selected movement analysis projects.
The internal combustion engine examined in terms of the four fundamental disciplines that determine its characteristics: 1) fluid mechanics; 2) chemistry of combustion and of exhaust emission; 3) first and second laws of thermodynamics, and 4) mechanics of reciprocating and rotary motion; high output Otto and Diesel engines for terrestrial, maritime and aerospace environments; normal and abnormal combustion; stratified charge and advanced low emission engines; hybrid and multifuel engines; Sterling and other space engines; free-piston and rotary-piston concepts and configurations.
Pharmaceutical manufacturing is vital to the success of the technical operations of a pharmaceutical company. This course is approached from the need to balance company economic considerations with the regulatory compliance requirements of safety, effectiveness, identity, strength, quality, and purity of the products manufactured for distribution and sale by the company. Overview of chemical and biotech process technology and equipment, dosage forms and finishing systems, facility engineering, health, safety and environment concepts, and regulatory issues.
This course reviews the 12 elements of the Process Safety Management (PSM) model created by the Center for Chemical Process Safety of the American Institute of Chemical Engineers. PSM systems were developed as an expectation/demand of the public, customers, in-plant personnel, stockholders and regulatory agencies because reliance on chemical process technologies were not enough to control, reduce and prevent hazardous materials incidents. PSM systems are comprehensive sets of policies, procedures and practices designed to ensure that barriers to major incidents are in place, in use and effective. The objectives of this course are to: define PSM and why it is important, describe each of the 12 elements and their applicability, identify process safety responsibilities, give real examples and practical applications to help better understand each element, share experiences and lessons learned of all participants, and assess the quality and identify enhancements to student's site PSM program.
An introduction to the principles and control of air pollution, including: types and measurement of air pollution; air pollution chemistry; atmospheric dispersion modeling; compressible fluid flow; particle dynamics; ventilation systems; inertial devices; electrostatic precipitators; scrubbers; filters; absorption and adsorption; combustion; condensation.
Current Good Manufacturing Practice compliance issues in design of pharmaceutical and biopharmaceutical facilities. Issues related to process flow, material flow, and people flow, and A&E mechanical, industrial, HVAC, automation, electrical, and computer. Bio-safety levels. Developing effective written procedures, so that proper documentation can be provided, and then documenting through validation that processes with a high degree of assurance do what they are intended to do. Levels I, II, and III policies. Clinical phases I, II, III and their effect on plant design. Defending products against contamination. Building quality into products.
Course addresses the sustainable operation and design of facilities and sites subject to regulatory requirements of US federal agencies such as FDA, NIH, OSHA, EPA, DOE and/or applicable international regulators. Course presents timely issues, challenges and potential benefits of implementing sustainable means and methods to meet new Green Codes and Design Standards that are either in draft review or final version for the regulated facility, whether in planning, design, construction or operation phase. Regulated buildings typically have their own unique requirements in their operation, which require special knowledge to comply and or mitigate safety and regulatory issues, while minimizing impact of rising energy costs to manufacturers, saving scarce resources, and protecting the environment. Furthermore, course introduces the students to resources, survey information of latest sustainable/Green thinking in Green Chemistry, Sustainability and Energy Efficient Design and Products to reduce waste, energy consumption, eliminate unnecessary or optimize manufacturing steps, cut operating costs and be environmentally sensitive. Topics include: Global trends in Green Regulations and Design Standards, history of “Sustainable Design,” examples of sustainability in large companies, site selection issues, water resource conservation, architectural issues and material selections, energy resource conservation and efficiency design for mechanical, electrical, and plumbing (MEP) systems in regulated facilities, energy performance of buildings, waste and environmental issues, material resource conservation and efficiency (disposables, packaging), construction techniques toward a sustainable certified facility, sustainable design for cGMP facilities and labs, building operations and maintenance. Course will provide useful, current and practical knowledge of Green and Sustainability Design and operation to individuals who are in or entering a technical career in regulated industries such as pharmaceutical, medical devices, and other sectors that have energy-intensive and regulated facilities.
This course provides a broad overview of topics related to the design and operations of modern biopharmaceutical facilities. It covers process, utilities, and facility design issues, and encompasses all major manufacturing areas, such as fermentation, harvest, primary and final purification, media and buffer preparation, equipment cleaning and sterilization, and critical process utilities. Unit operations include cell culture, centrifugation, conventional and tangential flow filtration, chromatography, solution preparation, and bulk filling. Application of current Good Manufacturing Practices and Bioprocessing Equipment Standards (BPE-2002) will be discussed.
Validation of a pharmaceutical manufacturing process is an essential requirement with respect to compliance with Good Manufacturing Practices (GMP) contained within the Code of Federal Regulations (21 CFR). Course covers validation concepts for plant, process, cleaning, sterilization, filtration, analytical methods, and computer systems; GAMP (Good Automated Manufacturing Practice), IEEE SQAP, and new electronic requirements - 21 CFR Part 11. Master validation plan, IQ, OQ, and PQ protocols, and relationships to GMP. National (FDA) and international (EU) regulatory affairs for cGMP (current Good Manufacturing Practice) and cGLP (current Good Laboratory Practice) requirements in development, manufacturing, and marketing. Handling the FDA inspection.
Computers and computerized systems are ubiquitous in pharmaceutical manufacturing. Validation of these systems is essential to assure public safety and compliance with appropriate regulatory issues regarding validation: GMP, GCP, 21CFR Part 11, etc. This course covers validation concepts for various classes of computerized systems and applications used in the pharmaceutical industry; importance of requirements engineering in validation; test protocols and design; organizational maturity considerations.
Analysis of refrigeration cycles, properties of refrigerants and coolants; psychrometry; factors affecting human comfort; environmental control requirements in industrial processes; estimation of infiltration and ventilation, heat transmission coefficients, insulation; heating and cooling load on buildings; numerical methods for building energy analysis; selection of air distribution systems, ducting and fans; selection of water and steam distribution systems, piping and pumps.
This course lays the foundations in aerospace engineering. Topics include the history of aviation, basic aerodynamics, airfoils, wings and other aerodynamic shapes, aircraft performance, stability and control, aircraft structures (structural analysis and materials), propulsion, flight test, rockets, space flight, and orbits.
Aerodynamic and thermodynamic fundamentals applicable to turbomachinery; design configurations and types of turbomachinery; turbine, compressor and ancillary equipment kinematics, thermodynamics and performance; selection and operational problems of turbomachinery.
This course presents validation for medical device manufacturers in terms of its objectives, strategies, planning, protocols, and documentation. Validation requirements include producing, collecting, analyzing, and managing data and documentation in support of medical device product design and product performance claims. These, as well as manufacturing processes and test methods, are presented within the context of current Quality System Regulations (QSR) as well as Risk Analysis. Qualification is addressed for equipment and operational systems, software and automated systems, and facilities for manufacturing medical devices. Validation in all life cycle phases is presented, both prior to commercial production and during the operating life of the plant, process, and product. Case studies are included as specific examples. Through this course, students will understand how to implement validation studies for medical device manufacturers and to evaluate existing studies.
Introduction to basic concepts and current state-of-the-art hardware; architecture and elementary programming; instruction sets; fundamental software concepts; interfacing microprocessors to external devices; microprocessors in control systems; hands-on laboratory applications of microprocessors in mechanical engineering systems.
An introduction to using a computer system to aid in engineering design, fundamental components of hardware and software; databases and database management, numerical control and computer-aided manufacturing. Integration of manufacturing system from conceptual design through quality control to final shipping is discussed. Applications include solids modeling, CAD drawing and solution using finite element method.
Course explores the current application of Lean Six Sigma in Pharmaceutical Manufacturing. Topics covered include: Lean Six Sigma Concepts and Techniques, Project and Team Dynamics, Tools of Lean Six Sigma and their Application, and Designing Pharmaceutical Processes for Lean Six Sigma. Emphasis is on DMAIC, including Define, Measure, Analyze, Improve, and Control methodology, with the students’ skill set developed through case studies and project work on actual pharmaceutical processes using statistical software (Minitab). At the conclusion of this course, students will understand the concepts and principles of Lean Six Sigma, be competent with Minitab software and be able to apply these techniques to pharmaceutical processes.
Application of mathematical optimization techniques, including linear and nonlinear methods, to design and manufacture of devices and systems of interest to mechanical engineers; optimization techniques include: constrained and unconstrained optimization in several variables, problems for structured multi-stage decision, and linear programming; formulation of design and manufacturing problems using computer- based methods; optimum design of parts and assemblies to minimize the cost of manufacture.
This course is involved in the design and development of parts and assemblies for manufacturability and functionality; characteristics and capabilities of significant manufacturing processes; principles of design for manufacturability; product planning; conceptual design; embodiment design; dimensional tolerances; optimum design of products to minimize cost of manufacture; materials specifications for ease of manufacturability and good functional results; design for ease of assembly; integrated product development; concurrent engineering practice.
Introduction to microsystem design, modeling and fabrication. Course topics include material properties of Microelectromechanical systems (MEMS), microfabrication technologies, structural behavior, sensing and actuation principles and methods. Emphasis on microsystems design, modeling and simulation including lumped element modeling and finite element analysis. The emerging nano-materials, processes and devices will also be discussed. Student teams design microsystems (sensors, actuators and sensing/control systems) of a variety of types, (optical MEMS, bioMEMS, inertial sensors, etc.) to meet a set of performance specifications using a realistic microfabrication process.
Early history of medical devices and procedures. Minimally invasive and open procedures, techniques and devices, including mechanical and electrosurgical devices. Manufacturing methods for catheters, balloons, plastic and metal components. Design of metal device components including material selection and strength and deformation adequacy using material properties and classical mechanics. Selection of insulation materials for and testing of electrosurgical devices. Selection of medical plastics and design elements. Balloon and catheter burst strength. The Poiseuille flow equation and its use for fluid flow through catheters and vessels. Rapid prototyping techniques, advantages and limitations. Understanding of biocompatibility testing and accelerated age testing using the Arrhenius equation. Device sterilization methods and testing. Developing a project plan from brainstorming to product release for a new device.
Bringing together the creative talents of electrical, mechanical, optical and chemical engineers, materials specialists, clinical-laboratory scientists, and physicians, the science of biomedical microelectromechanical systems (Bio MEMS) promises to deliver sensitive, selective, fast, low cost, less invasive, and more robust methods for diagnostics, individualized treatment, and novel drug delivery. The goals of this course are to introduce microfabrication, microfluidics, sensors, actuators, drug delivery systems, micro total analysis systems and lab-on-a-chip devices, detection and measurement systems. The main focus is on the fundamental challenges and limitations involved in designing and demonstrating BioMEMS devices.
This course offers concurrent design as they apply to quiet product design; vibration and acoustic characteristics in design or products and systems; source-path-receiver model for vibration and acoustics; vibration of single and two degrees of freedom models; features of continuous systems, design for low vibration and vibration control; acoustic plane and spherical waves; acoustical source models; acoustic performance descriptions; design of quiet products and systems; application of computational methods; case studies.
Focus of the course is compliance requirements necessary for Good Manufacturing Practices and Quality Management System. Background includes familiarization of the different categories of medical devices and their manufacturing special requirements. Manufacturing facility requirements are then presented, noting major differences between the various classes of medical devices and also within the classes (e.g. sterility requirements or cleanliness). Included are special requirements for combination products. Regulatory requirements are reviewed. The core of this course is the good engineering practices of facility design. This includes conceptual design, basic engineering, scale up (from lab to manufacturing), procurement, construction, key technologies such as HVAC and utilities requirements, and commissioning, qualification, and validation. Calibration, re-qualification, and maintenance are covered for optimal operational efficiency. Case studies of various manufacturing facilities will be presented.
This course is a graduate-level introduction to Human Factors Engineering, the discipline that examines the interactions between humans and other elements of a system. The course will present theory, principles, data and methods to design for humans ranging from infants to the aged with special attention to their biological and physical needs. Achieving optimal person- environment interaction requires knowledge about the broad range of human functional capacity, including – but not limited to – anthropometry, biomechanics, sensory processes and others. The course involves a project that applies the obtained knowledge to real world problems with innovative product designs. Undergraduate-level statics and dynamics are required; knowledge of engineering controls is recommended.
Review of laws regarding air, water and noise pollution. Role of engineering representing a company or public before government agencies. Permit system, implementation plans, and other legal sanction. Site studies and environmental impact statements.
Problems in mechanical engineering illustrating the application of computer methods to solve roots of algebraic and transcendental equations, system of algebraic equations, curve fitting, numerical integration and differentiation, ordinary and partial differential equations.
Basic principles of heat exchanger design; types of heat exchangers, heat exchanger effectiveness; uncertainty analysis of design and operating parameters; fouling factors; heat transfer augmentation in heat exchangers, two-phase flow, boiling and condensation in heat exchangers, second law of thermodynamics for optimization of heat exchanger design; tube vibrations; codes and standards; individually supervised heat exchanger design project.
Introduction to electronic packaging, thermal characteristics and operating environment of electronic components, reliability; fundamental concepts and basic modes of heat transfer; contact and interface thermal resistance; convective cooling of components and systems, modeling of chips, packages, and printed circuit boards; finned array and heat sink analysis; cold plate and heat exchanger design and analysis; computer-aided design; heat pipes; liquid and immersion cooling.
This is a multi-disciplinary course in the analysis and design of electronic systems. Topics include: introduction to conduction, convection and radiation heat transfer as applied to electronic systems; design of heat sinks for small to large frames; structural analysis including shock and vibration modeling; introduction to electromagnetic shielding; integrated product design for manufacturing, reliability and quality control.
Elements of a robotic/flexible automation system; overview of applications; manipulator anatomy; drive systems; end effectors; sensors; computer control: functions, levels of intelligence, motion control, programming and interfacing to sensors and actuators; applications: identification, hardware selection, work cell design, economics, case studies; design of parts and assemblies; advanced topics.