CHE 501 Mass and Energy Balances, Stagewise OperationsClose
This course serves as an introduction to chemical engineering for those with no previous training in the field. Among the topics covered are mass and energy balances and equilibrium stagewise operations. No credit for graduate CHE majors. |
|
CHE 502 Transport PhenomenaClose
This introductory course in chemical engineering covers mass, heat and momentum transfer. A background in ordinary and partial differential equations is required. No credit for graduate CHE majors. |
|
CHE 531 Process Safety ManagementClose
This course addresses management and engineering design concepts required for process safety in chemical and biotechnology systems, with pharmaceutical manufacturing applications. The basis for the course is a Process Safety Management (PSM) model from OSHA and the Center for Chemical Process Safety of AICHE . Content focuses on sound engineering principles and practices as they apply to industrial situations, project design, risk mitigation, process, and equipment integrity, and engineering codes and standards. Includes calculation of risk assessment scores and cost justification factors; HASOPs studies using P&IDs; sizing safety valves, rupture discs, explosion venting, and emergency scrubbers; MSDS applied to dispersion modeling; overall control, reduction, and prevention of hazardous materials incidents; and case studies. |
|
ChE 539 / PME 539 Bioprocess Technology in API ManufacturingClose
This course provides a broad overview of topics related to the design and operations of modern biopharmaceutical facilities. It covers process, utilities, and facility design issues, and encompasses all major manufacturing areas, such as fermentation, harvest, primary and final purification, media and buffer preparation, equipment cleaning and sterilization, and critical process utilities. Unit operations include cell culture, centrifugation, conventional and tangential flow filtration, chromatography, solution preparation, and bulk filling. Application of current Good Manufacturing Practices and Bioprocessing Equipment Standards (BPE-2002) will be discussed. |
|
CHE 564 Microprocessors in Process ControlClose
Designed to provide the process engineers with the background necessary to understand and work with microprocessor-based systems. Topics include: introduction and overview of microprocessor-based technology in chemical engineering; analog and digital signal conditioning, data transmission and serial interfacing using RS-232C and GPIB IEEE-488 standards; analog-to-digital conversion and sampling; digital-to-analog conversion; digital I/O, switches/relays and power supplies; microprocessor-based sensors, transducers and actuators; programmable logic controllers and batch process control; software packages for data-acquisition and control. Prerequisites: Undergraduate Course in circuits and process control. |
|
ChE 610 Process Synthesis, Analysis and DesignClose
Development and evaluation of processing schemes; analysis of process circuits; establishing design criteria; process design; evaluation and selection of process equipment; economic analysis and evaluation; applications to chemical, biochemical, waste treatment, energy and other processes of current interest. |
|
ChE 611 Design of Separation ProcessesClose
Selection, design and scaling of separation processes using principles of momentum, energy and mass transfer; applications to novel as well as to conventional separation techniques. |
|
ChE 612 Stagewise OperationsClose
The ultimate goal of this course is to prepare students to undertake the analysis of the most difficult problems in equilibrium stage operations. The problems typically involve one or more columns with components exhibiting highly non-ideal behavior. This class of problems includes azeotropic distillation, extractive distillation, columns with more than one liquid phase and a variety of other anomalies. Lack of complete equilibrium data is not uncommon. Extensive use is made of commercial software in the solution of problems. The course concludes with the assignment of an industrial problem, a substantial project, which requires that the students exercise virtually all techniques studied. |
|
CHE 615 / NANO 615 Separation ProcessesClose
This course provides an overview and industrial perspectives regarding downstream separation in drug substance development and manufacturing. Basic principles and practical applications of unit operations most commonly employed in the pharmaceutical industry will be discussed, including extraction, absorption, membrane, distillation, crystallization, filtration, and drying. Examples will be discussed to illustrate the intrinsic relationship between process development, equipment selection, and scale-up success. |
|
ChE 620 Chemical Engineering ThermodynamicsClose
This course supplements the classical undergraduate thermodynamics course by focusing on physical and thermodynamic properties and phase equilibria. A variety of equations of state, and their applicability, are introduced as are all of the important liquid activity coefficient equations. Customization of both vapor and liquid equations is introduced by appropriate methods of applied mathematics. Vapor-liquid, liquid-liquid, vapor-liquid-liquid and solid-liquid equilibria are considered with rigor. Industrial applications are employed. A variety of methods for estimating physical and thermodynamic properties are introduced. Students are encouraged to use commercial software in applications. The course concludes with an introduction to statistical thermodynamics. |
|
CHE 621 / PME 621 Pharmaceutical MixingClose
Fundamentals of mixing relevant to pharmaceutical engineering, flow patterns, dead zones, components of mixers, importance of baffling, determination of flow, power, and shear rates, effect of rheology, “shaken, not stirred”, why viscosity affects more than just Reynolds numbers, continuous processing, heat transfer, suspending solids that sink or float, wetting out solids, concepts of crystallization, catalysis, mass transfer, liquid-liquid dispersions, emulsions, and separations, fermenters, hydrogenators, other gas-liquid applications, pit-falls of scale-up, why scale-down is the better way to design, process intensification and solids-solids mixing. |
|
ChE 630 / PME 639 Theory of Transport ProcessesClose
Generalized approach to differential and macroscopic balances: constitutive material equations; momentum and energy transport in laminar and turbulent flow; interphase and intraphase transport; dimensionless correlations. |
|
ChE 639 / PME 639 Modeling and Simulation of Pharmaceutical Manufacturing SystemsClose
This course will review identification of pharmaceutical processes and systems, model formulation, algorithm development, and solution techniques of relevance to pharmaceutical manufacturing. Development of concepts and analysis skills necessary for modeling and simulation of pharmaceutical manufacturing processes and systems are emphasized. Overview of modeling techniques, process model development, product and assembly models, optimization techniques, and methods used in decision analysis, including multi-attribute utility models, decision trees, and discrete event simulation is presented. Prerequisite: undergraduate degree in engineering or its equivalent. |
|
ChE 641 New Separation ProcessesClose
The course begins with a review of traditional separation processes such as distillation, evaporation, extraction, crystallization and absorption. New topics in separation which are covered include pressure swing adsorption, molecular sieves, ion exchange, reverse osmosis, microfiltration, nanofiltration, ultrafiltration, diafiltration, gas permeation, pervaporation, supercritical fluid extraction and liquid chromatography. Industrial applications, design considerations and engineering analysis of these separation topics are covered. |
|
ChE 650 Reactor DesignClose
Analysis of batch and continuous chemical reactions for homogeneous, heterogeneous, catalytic and noncatalytic reactions; influence of temperature, pressure, reactor size and type, mass and heat transport on yield and product distribution; design criteria based on optimal operating conditions and reactor stability will be developed. |
|
ChE 660 Advanced Process ControlClose
Mathematical modeling and identification of chemical processes. State-space process representation and analysis: stability, observability, controllability and reachability. Analysis and design of advanced control systems: internal model control, dynamic matrix control and model predictive control. Synthesis of multivariable control systems: interaction analysis, singular value decomposition, decoupler design. Continuous and sampled-data systems, on-line process identification. State and parameter estimation techniques: Luenberger observer and Kalman filter. Knowledge of Laplace transforms, material and energy balances, computer programming and matrix algebra is required. |
|
CHE 661 / ME 623 Design of Control SystemsClose
This course focuses on the application of advanced process control techniques in pharmaceutical and petrochemical industries. Among the topics considered are bioreactor and polymerization reactor modeling, biosensors, state and parameter estimation techniques, optimization of reactor productivity for batch, fed-batch and continuous operations, and expert systems approaches to monitoring and control. An overview of a complete automation project - from design to startup - of a pharmaceutical plant will be discussed. Included: process control issues and coordination of interdisciplinary requirements and regulations. Guest speakers from local industry will present current technological trends. A background in differential equations, biochemical engineering, and basic process control is required. |
|
ChE 662 Chemical Process SimulationClose
The course comprises a series of workshops, employing an industrial process simulator, Aspen Plus, which explore the primary components required to simulate a chemical process. Most workshops have embedded irregularities designed to heighten the student-awareness of the types of errors that could arise when using simulation software. The workshops include facilities to exercise and customize a wide variety of physical and thermodynamic properties as the students develop process models. Heavy concentration is on the equations describing the models used. As the experience level of the students rises, workshops designed to introduce complicated industrial flowsheets are employed. |
|
ChE 670 / MT 670 Polymer Properties and StructureClose
Stress-strain relationships, theory of linear viscoelasticity and relaxation spectra, temperature dependence of viscoelastic behavior, dielectric properties, dynamic mechanical and electrical testing, molecular theories of flexible chains, statistical mechanics and thermodynamics of rubber-like undiluted systems, morphology of high polymers. |
|
| CHE 671 Polymer RheologyClose
Molecular and continuum mechanical constitutive equations for viscoelastic fluids; analysis of viscometric experiments to evaluate the viscosity and normal stress functions; dependence of these functions on the macromolecular structure of polymer melts; solution of isothermal and nonisothermal flow problems with non-Newtonian fluids which are encountered in polymer processing; development of design equations for extruder dies and molds. |
|
CHE 672 Processing of Polymers for Biomedical ApplicationsClose
Descriptions of various polymer processing operations and processing requirements of biomedical products, principles of processing of polymers covering melting, pressurization, mixing, devolatilization, shaping using extrusion, spinning, blowing, coating, calendering and molding technologies, surface treatment and sterilization, applications in the areas of prostheses and artificial organs and packaging of various biomedical devices. |
|
ChE 675 Polymer Blends and CompositesClose
Recent advances in polymer blend and composite formation; the role of melt rheology in component selection and the resulting morphology; melt mixing processes and equipment; models for predicting processing and performance characteristics; morphology generation and control in manufacturing processes; sample calculations and case histories for polyblends used in film blowing, blow molding and injection molding. |
|
ChE 676 Polymer Mold and Die DesignClose
Principal manufacturing methods utilizing molds and dies; mold and die design characteristics dictated by functional requirements; interaction between molds/dies and processing machinery; mathematical models of forming processes, including flow through dies and into molds, solidification, heat transfer, and reaction (in reactive processing); end-product properties (morphology, bulk properties, tolerances, and appearance) and operating conditions in alternative manufacturing methods; materials and manufacturing methods for molds and dies; and case studies. |
|
ChE 677 Polymer Product DesignClose
Design of polymeric products; design criteria based upon product functions and geometry; material selection by property assessment; selection of molds, dies, and special manufacturing devices (e.g., mold inserts); selection of appropriate forming process (injection, rotational or blow-molding, extrusion, etc.); and determination of optimum operating conditions (such as temperature, pressure, cycle, or residence time). Case histories of failure. |
|
ChE 678 Experimental Methods in Polymer Melt RheologyClose
Discussion of models for flow and deformation in polymers, and a treatment of measurable rheological properties. Analysis of thermoplastic and thermosetting resins for processability. Use of experimental data to determine parameters of the constitutive equations. Laboratory includes use of state-of-the-art equipment in elongational, rotational and capillary viscometry. |
|
CHE 681 Pharmaceutical Reaction EngineeringClose
This course will provide a fundamental understanding, and the application of emerging and current approaches to reaction engineering and catalysis in the pharmaceutical and fine chemical industries. The course will focus on promising technologies such as enzymatic catalysis and bioreactor design, chiral synthesis and kinetics, multiphase reactions, and microreactor technology with emphasis throughout on industrially relevant reactions. |
|
CHE 682 Colloids and Interfacial PhenomenaClose
A survey course covering the chemical, biological and material science aspects of interfacial phenomena. Applications to adhesion, biomembranes, colloidal stability, detergency, lubrication, coatings, fibers and powders - where surface properties play an important role. |
|
ChE 695 / BME 695 Bio/Nano PhotonicsClose
This course deals with the principles of light interactions with biological and biomedical-relevant systems. The enabling aspects of nanotechnology for advanced biosensing, medical diagnosis, and therapeutically treatment will be discussed. |
|
ChE 700 / BME 700 Seminar in Chemical EngineeringClose
Lectures by department faculty, guest speakers, and doctoral students on recent research. Enrollment during the entire period of study is required of all full-time students. No credit. Must be taken every semester. |
|
ChE 703 Numerical Methods in Chemical EngineeringClose
The course is designed to enable students to attack a variety of chemical engineering problems which lend themselves to solution by numerical methods as opposed to classical mathematics. Problems that do not fit the mold "using existing software" are illustrated. The students are encouraged to create their own software to solve problems. For this purpose, students are given an introduction to the Visual Basic programming language. Students are also encouraged to use more advanced methods in Excel. Examples and homework assignments are drawn from industrial experience when possible. |
|
|
Print