BME 306 Introduction to Biomedical EngineeringClose Overview of the biomedical engineering field with applications relevant to the healthcare industry such as medical instrumentation and devices. Introduction to the nervous system, propagation of the action potential, muscle contraction and introduction to the cardiovascular system. Discussion of ethical issues in biomedicine. Prerequisite: Sophomore Standing. |
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BME 322 Engineering Design VIClose Introduction to the principles of wireless transmission and the design of biomedical devices and instrumentation with wireless capabilities.(e.g. pacemakers, defibrilators. EKG). Electrical safety (isolation, shielding), and equipment validation standards for FDA compliance are introduced. Use of LabView to provide virtual bioinstrumentation. The course culminates in group projects to design a biomedical device that runs on wireless technology. |
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BME 342 Transport in Biological SystemsClose A study of momentum, mass and heat transport in living systems. Rheology of blood. Basic hemodynamics. Use of the equations of continuity and motion to set up complex flow problems. Flow within distensible tubes. Shear stress and endothelial cell function. Mass transfer and metabolism in organs and tissues. Microscopic and macroscopic mass balances. Diffusion. Blood-tissue transport of solutes in the microcirculation. Compartmental models for pharmacokinetic analyses. Analysis of blood oxygenators, hemodialysis, tissue growth in porous support materials. Artificial organs. Energy balances and the use of heat to treat tumor growth (radio frequency ablation, cryogenic ablation). Laboratory exercises accompany major topics discussed in class and are conducted at the same time. |
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BME 423 Senior Design IClose Senior design courses. Senior design provides, over the course of two semesters, a collaborative design experience with a significant biomedical problem related to human health. The project will often originate with an industrial sponsor or a medical practitioner at a nearby medical facility and will contain a clear implementation objective (i.e. for a medical device). It is a capstone experience that draws extensively on the student’s engineering and scientific background and requires independent judgments and actions. The project generally involves a determination of the medical need, a detailed economic analysis of the market potential, physiological considerations, biocompatibility issues, ease of patient use, an engineering analysis of the design, manufacturing considerations and experimentation and/or prototype construction of the device. The faculty advisor, industrial sponsor or biomedical practitioner works closely with the group to insure that the project meets its goals in a timely way. Leadership and entrepreneurship are nourished throughout all phases of the project. The project goals are met in a stepwise fashion, with each milestone forming a part of a final report with a common structure. Oral and written progress reports are presented to a panel of faculty at specified intervals and at the end of each semester. |
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BME 424 Senior Design IIClose Senior design courses. Senior design provides, over the course of two semesters, a collaborative design experience with a significant biomedical problem related to human health. The project will often originate with an industrial sponsor or a medical practitioner at a nearby medical facility and will contain a clear implementation objective (i.e. for a medical device). It is a capstone experience that draws extensively on the student’s engineering and scientific background and requires independent judgments and actions. The project generally involves a determination of the medical need, a detailed economic analysis of the market potential, physiological considerations, biocompatibility issues, ease of patient use, an engineering analysis of the design, manufacturing considerations and experimentation and/or prototype construction of the device. The faculty advisor, industrial sponsor or biomedical practitioner works closely with the group to insure that the project meets its goals in a timely way. Leadership and entrepreneurship are nourished throughout all phases of the project. The project goals are met in a stepwise fashion, with each milestone forming a part of a final report with a common structure. Oral and written progress reports are presented to a panel of faculty at specified intervals and at the end of each semester. |
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BME 445 Biosystems Simulation and ControlClose Time and frequency domain analysis of linear control systems. Proportional, derivative and integral control actions. Stability. Applications of control theory to physiological control systems: biosensors, information processors and bioactuators. Mathematical modeling and analysis of heart and blood pressure regulation, body temperature regulation, regulation of intracellular ionic concentrations, eye movement and pupil dilation controls. Use of Matlab and Simulink to model blood pressure regulation, auto regulation of blood flow, force development by muscle contraction, and integrated response of cardiac output, blood pressure and respiration to exercise. |
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BME 453 BioethicsClose This course focuses on professional ethical conduct in the biomedical field. It will enable students to understand the ethical challenges they may encounter as biomedical engineers, allow them to practice biomedical engineering in an ethical manner and conduct themselves ethically as contributing members of society. Case discussions and presentations by practitioners in the field illustrate ethical norms and dilemmas. |
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| BME 482 Engineering PhysiologyClose Introduction to mammalian physiology from an engineering point of view. The quantitative aspects of normal cellular and organ functions and the regulatory processes required maintaining organ viability and homeostasis. Laboratory exercises using exercise physiology as an integration of function at the cellular, organ and systems level will be conducted at the same time. Measurements of heart activity (EKG), cardiac output (partial CO2 rebreathing), blood pressure, oxygen consumption, carbon dioxide production, muscle strength (EMG), fluid shifts and respiratory function in response to exercise stress will be measured and analyzed from an engineering point of view. |
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BME 498 Research in Biomedical Engineering IClose Individual investigation of a substantive character undertaken at an undergraduate level under the guidance of a member of the departmental faculty. A written report is required. Hours to be arranged with the faculty advisor. Prior approval required. These courses can be used as general electives for degree requirements. |
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BME 499 Research in Biomedical Engineering IIClose Individual investigation of a substantive character undertaken at an undergraduate level under the guidance of a member of the departmental faculty. A written report is required. Hours to be arranged with the faculty advisor. Prior approval required. These courses can be used as general electives for degree requirements. |
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BME 504 / CPE 585 Medical Instrumentation and ImagingClose Imaging plays an important role in both clinical and research environments. This course presents both the basic physics together with the practical technology associated with such methods as X-ray computed tomography (CT), magnetic resonance imaging (MRI), functional MRI (f-MRI) and spectroscopy, ultrasonics (echocardiography, Doppler flow), nuclear medicine (Gallium, PET and SPECT scans) as well as optical methods such as bioluminescence, optical tomography, fluorescent confocal microscopy, two-photon microscopy and atomic force microscopy. |
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BME 505 / MT 505 BiomaterialsClose Intended as an introduction to materials science for biomedical engineers, this course first reviews the materials properties relevant to the their application to the human body. It goes on to discuss proteins, cells, tissues, and their reactions and interactions with foreign materials, as well as the degradation of these materials in the human body. The course then treats various implants, burn dressings, drug delivery systems, biosensors, artificial organs, and elements of tissue engineering. Laboratory exercises accompany the major topics discussed in class and are conducted at the same time. |
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BME 506 BiomechanicsClose This course reviews basic engineering principles governing materials and structures such as mechanics, rigid body dynamics, fluid mechanics and solid mechanics and applies these to the study of biological systems such as ligaments, tendons, bone, muscles, joints, etc. The influence of material properties on the structure and function of organisms provides an appreciation for the mechanical complexity of biological systems. Methods for both rigid body and deformational mechanics are developed in the context of bone, muscle, and connective tissue. Multiple applications of Newton's Laws of mechanical are made to human motion. |
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