BME 503 Physiological SystemsClose
Introduction to mammalian physiology from an engineering point of view. The quantitative aspects of normal cellular and organ functions and the regulatory processes required to maintain organ viability and homeostasis. Laboratory exercises using exercise physiology as an integration of function at the cellular, organ and systems level will be conducted at the same time. Measurements of heart activity (EKG), cardiac output (partial CO2 rebreathing), blood pressure, oxygen consumption, carbon dioxide production, muscle strength (EMG), fluid shifts and respiratory function in response to exercise stress will be measured and analyzed from an engineering point of view. |
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BME 557 Sensory Systems IClose
The Sensory Systems I course will focus on speech, audition, and vision systems. Students will begin with a review of system principles including sampling, filtering, analog to digital conversion (ADC), spectral (Fourier) analysis and transfer functions. The second topic will cover the audio spectrum and properties of sound as they relate to both speech and hearing. The course will then cover basic anatomy and physiology of the larynx, ear, and eye. Students will participate in two types of Labs for each of the three topics. Sensory Labs are designed to enhance the student’s knowledge of sound production, auditory response and image processing. Reverse Engineering (RE) Labs utilizing existing speech, hearing, and vision enhancement products will be conducted as well. |
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BME 600 Strategies and Principles of Biomedical DesignClose
A successful approach to product development and design in the field of medical technologies requires a highly interdisciplinary approach. This course reviews the regulations, protocols, and guidelines which must be met in each discipline, and describes how these issues are inter-related and how the affect design and product development. Marketing, Regulatory, IP and Clinical aspects are all considered in the technical aspects of design. |
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BME 601 Advanced Biomedical Engineering LabClose
One of the distinguishing features of biomedical engineers is the ability to make and interpret measurements on living systems. One of the major objectives of advanced laboratory training is to provide experience in selecting appropriate measurement and analysis tools that will advance hypothesis driven and translational research and development. This laboratory serves these dual purposes. Students are introduced to techniques for measurements at the cellular, organ and systems levels. Students will then use these techniques to: a) formulate hypotheses, design experiments using the tools provided, make appropriate measurements, analyze the data an determine if the data do or do not support their hypotheses; b) make measurements that facilitate the design and manufacture of devices in terms of materials properties, fatigue and failure modes. Each student will keep a laboratory notebook. |
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BME 602 Principles of Tissue EngineeringClose
This course is an introduction to the field of Tissue Engineering. It is rapidly emerging as a therapeutic approach to treating damaged or diseased tissues in the biotechnology industry. In essence, new and functional living tissue can be fabricated using living cells combined with a scaffolding material to guide tissue development. Such scaffolds can be synthetic, natural, or a combination of both. This course will cover the advances in the field of cell biology, molecular biology, material science and their relationship towards developing novel 'tissue engineered' materials. |
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BME 603 Topics in Biological TransportClose
The engineering applications of biological transport phenomena are important considerations in basic research related to molecules, organelles, cell and organ function; the design and operation of devices such as filtration units for kidney dialysis, high density cell culture and biosensors; and applications including drug and gene delivery, biological signal transduction and tissue engineering. This course develops the fundamental principles of transport processes, the mathematical expression of these principles and the solution of transport equations, along with characterization of composition, and function of living systems to which they are applied. |
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BME 650 / NANO 650 Advanced BiomaterialsClose
Upon completion of this course, students will be able to demonstrate an understanding of the major classes of engineering materials, their principle properties and design requirements that serve as both the basis for materials selection as well as for the ongoing development of new materials. This course is substantially differentiated from introductory materials courses by its very specific focus on material whose use puts them in direct contact with physiological systems. Thus the course begins with brief sections on inflammatory response, thrombosis, infection and device failure. It then concentrates on developing the fundamental material science and engineering concepts underlying the structure-property relationships in both synthetic and natural polymers, metals and alloys, and ceramics relevant to in vivo medial-device technology. |
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BME 655 Principles of Multiscale Biosystems Development and IntegrationClose
This course extends concepts present in tissue engineering, biotransport and biomaterial to develop design principles for generating tissue and organs in-vitro. The processes which cells integrate proteins and extracellular matrix to form functioning organ systems are developed. The principles of bioreactor design are sued to analyze and design in-vitro systems for growing functioning tissue and organs for use as prostheses. Principles of Scale-up to organs of different size are discussed. Design issues and limitations for extension of these principles to multi-organ systems are illustrated. |
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BME 665 PathophysiologyClose
Pathophysiology describes changes in physiology resulting in disease or injury. A solid understanding of normal physiology is necessary before attempting the study of abnormal situations. The course emphasizes the "mechanistic" approach to pathophysiology, i.e., A-B-C, rather that the symptom-diagnosis-treatment approach. Multiple examples, case studies and procedural videos are presented with a discussion of what they do well and where improvements can be made. |
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BME 675 / NANO 675 NanomedicineClose
This course will provide a comprehensive introduction to the rapidly developing field of nanomedicine, and discuss the application of nanoscience and nanotechnology in medicine such as in diagnosis, imaging and therapy, surgery and drug delivery. |
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| BME 685 / NANO 685 NanobiotechnologyClose
This course describes the application of nano- and micro-fabrication methods to build tools for exploring the mysteries of biological systems. It is a graduate-level course that will cover the basics of biology and the principles and practice of nano- and micro-fabrication techniques with a focus on applications in biomedical and biological research. |
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BME 690 / CH 690 Cellular Signal TransductionClose
This advanced course coves the mechanism and biological role of signal transduction in mammalian cells. Topics included are exracellular regulatory signals, intercellular signal transduction pathways, role of tissue context in the function of cellular regulation, and example of biological processes controlled by specific cellular signal transduction pathways. |
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BME 695 / CHE 695 Bio/Nano PhotonicsClose
This course deals with the principles of light interactions with biological- and biomedical-relevant systems. The enabling aspects of nanotechnology for advanced biosensing, medical diagnosis, and therapeutically treatment will be discussed. |
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