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 | | Nuran M. Kumbaraci | | Associate Professor, Chemical Biology |  | | School: | Schaefer School of Engineering & Science | | Department: | Chemistry, Chemical Biology & Biomedical Engineering | | Program: | Chemistry & Chemical Biology
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| | Location: | 417 McLean Chemical Sciences Building | | Phone: | 201.216.5554 | | Fax: | 201.216.8240 | | Email: | nkumbara@stevens.edu |
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CH 281:Biology and Biotechnology
Biological principles and their physical and chemical aspects are explored at the cellular and molecular level. Major emphasis is placed on cell structure, the processes of energy conversion by plant and animal cells, genetics and evolution, and applications to biotechnology. |
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CH 282:Introductory Biology Laboratory
An introductory laboratory illustrating basic techniques and principles of modern biology by means of laboratory experiments and simulated experiments. This laboratory does not satisfy medical school admission requirements. |
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CH 381:Cell Biology
The structure and function of the cell and its subcellular organelles is studied. Biological macromolecules, enzymes, biomembranes, biological transport, bioenergetics, DNA replication, protein synthesis and secretion, motility, and cancer are covered. Cell biology experiments and interactive computer simulation exercises are conducted in the laboratory. |
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CH 382:Biological Systems
Physiochemical principles underlying the coordinated function in multicellular organisms are studied. Electrical properties of biological membranes, characteristics of tissues, nerve-muscle electrophysiology, circulatory, respiratory, endocrine, digestive, and excretory systems are covered. Computer simulation experiments and data acquisition methods to evaluate and monitor human physiological systems are conducted in the laboratory. |
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CH 484:Introduction to Molecular Genetics
Introduction to the study of molecular basis of inheritance. Starts with classical Mendelian genetics and proceeds to the study and function of DNA, gene expression and regulation in prokaryotes and eukaryotes, genome dynamics and the role of genes in development, and cancer. All topics include discussions of current research advances. Accompanied by laboratory section that explores the lecture topics in standard wet laboratory experiments and in computer simulations. |
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CH 583:Physiology
Fundamentals of control processes governing physiological systems analyzed at the cellular and molecular level. Biological signal transduction and negative feedback control of metabolic processes. Examples from sensory, nervous, cardiovascular, and endocrine systems. Deviations that give rise to abnormal states; their detection, and the theory behind the imaging and diagnostic techniques such as MRI, PET, SPECT; and the design and development of therapeutic drugs. The principles, uses, and applications of biomaterials and tissue engineering techniques; and problems associated with biocompatibility. Students (or groups of students) are expected to write and present a term project. |
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CH 684:Molecular Biology Laboratory Techniques
This laboratory course introduces essential techniques in molecular biology and genetic engineering in a project format. The course includes aseptic technique and the handling of microbes; isolation and purification of nucleic acids; construction, selection and analysis of recombinant DNA molecules; restriction mapping; immobilization and hybridization of nucleic acids; and labeling methods of nucleic acid probes. |
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CH 686:Immunology
The cells and molecules of the immune system and their interaction and regulation; the cellular and genetic components of the immune response, the biochemistry of antigens and antibodies, the generation of antibody diversity, cytokines, hypersensitivities, and immunodeficiencies (i.e. AIDS); and transplants and tumors. Use of antibodies in currently emerging immunodiagnostic techniques such as ELISA, disposable kits, molecular targets, and development of vaccines utilizing molecular biological techniques, such as recombinant and subunit vaccines. Students (or groups of students) are expected to write and present a term project. |
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CH 900:Masters Thesis in Chemistry/Chemical Biology
For the degree of Master of Science, five to ten credits with departmental approval. |
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CH 496:Chemistry Project I
Participation in a small group project, under the guidance of a faculty member, whose prior approval is required. Experimentation, application of chemical knowledge and developmental research leading to the implementation of a working chemical process. Individual or group written report required. |
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CH 497:Chemistry Project II
Participation in a small group project, under the guidance of a faculty member, whose prior approval is required. Experimentation, application of chemical knowledge and developmental research leading to the implementation of a working chemical process. Individual or group written report required.
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CH 781:Selected Topics in Biochemistry II
Topics of current interest in biochemical research are discussed, such as: enzyme chemistry, biochemical genetics and development, cellular control mechanism, biochemistry of cell membranes, bioenergetics, and microbiology.
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| | Research & Education | |
| | Education | - Post-Doctoral Research: Columbia University, New York, NY, College of Physicians and Surgeons, Neurophysiology and Cellular Biophysics
- Ph.D., M.Phil., M.A., Physiology, College of Physicians and Surgeons, Columbia University, New York, NY
- M.S., Chemical Engineering, Columbia University, New York, NY
- B.S., Chemistry, Robert College, Istanbul
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| | | Research | - Developing and applying chemical methods to study biological problems in the areas of proteomics and microarray technologies
- Neuromuscular physiology, biochemistry and biophysics of muscle contraction, synaptic transmission, immunochemical mechanisms
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| | Experience & Service | |
| | General Information | Dr. Kumbaraci is the advisor for the Accelerated Chemical Biology Program, Chemical Biology Program, and an advisor for the Graduate Chemical Biology Program. She has been on the Stevens Faculty since 1979. | | Professional Service | - APS -- American Physiological Society
- SFN -- Society for Neuroscience
- National Association of Advisors for the Health Professions
- Sigma Xi -- Honorary Research Society
- Phi Lambda Epsilon -- Honorary Chemistry Society
- AED -- National Honorary Premedical Society
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| | | Experience | Stevens Institute of Technology, Associate Professor, 1979-present Barnard/Columbia College and NYU, Organic Chemistry, Biology Instructor Artificial Organs Research Laboratory, Columbia University, New York, NY Lever Brothers Headquarters, New York, NY, Pharmaceutical Marketing Siemens und Halske, Germany, Electrodeposition Laboratory Eczacibasi Pharmaceutical Co., Analytical Research and Product Development Chemist
*Patents on Aerosol and Liquid Pharmaceutical Products |
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| | Achievements & Professional Societies | |
| | Honors & Awards | - NIH-Postdoctoral Fellowship
- NIH-Predoctoral Fellowship
- ESSO Academic Scholarship
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| | | Grants, Contracts & Funds | - NSF-1979-1985: Honors Courses and Workshops for Pre-College Teachers of Science in Modern Biology
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| | Selected Publications | |
| Books
Nuran M. Kumbaraci. (2008). Chemical Biology Laboratory, Wiley.
Journals
N. M. Kumbaraci, W. L. Nastuk. "Action of Caffeine in Excitation-Contraction Coupling of Frog Skeletal Muscle Fibres", The Journal of Physiology, 325 (1), 195-211.
N. M. Kumbaraci, W.L. Nastuk. "Effects of Δ9-Tetrahydrocannabinol on Excitable Membranes and Neuromuscular Transmission", Molecular Pharmacology, 17, 344-349.
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