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 | | Chandima Abeywickrama | | Assistant Professor, Chemistry |  | | School: | Schaefer School of Engineering & Science | | Department: | Chemistry, Chemical Biology & Biomedical Engineering | | Program: | Chemistry & Chemical Biology
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| | Location: | 303 McLean Hall | | Phone: | 201-216-5547 | | Fax: | 201-216-8240 | | Email: | cabeywic@stevens.edu |
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CH 244:Organic Chemistry II
Continuation of CH 243; reactions of aromatic compounds; infrared and nuclear magnetic resonance spectroscopy. |
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CH 640:Advanced Organic and Heterocyclic Chemistry I
An advanced course in the chemistry of carbon compounds, with special reference to polyfunctional compounds, heterocycles, techniques of literature survey, stereochemical concepts, and physical tools for organic chemists. Fall semester. |
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| | Research & Education |  |
| | Education | Post Doctoral Research Scientist, Columbia University New York, NY 2005-2008, Chemistry Department & Genome Center -Training under Prof. Koji Nakanishi & Prof. Jingyue Ju Ph.D. (Organic Chemistry), City University of New York, New York, NY - 2004 B.Sc. Chemistry Honors, University of Colombo, Faculty of Science, Sri Lanka - 1996 Chemistry Honors, Royal Society of Chemistry (Institute of Chemistry, Sri Lanka), Sri Lanka - 1993 | | Research | | We are Bio-organic/ Medicinal chemistry group interested in the "Design, Synthesis and Evaluation of Biological Active Molecules”. Our focus is on synthesizing novel heterocyclic molecules as new therapeutic approaches for cancer and infectious diseases. We plan to develop new compounds that can induce cell differentiation and could act as potential anti-cancer agents. Molecular modeling studies and bioassays will be used to design and characterize the most potent inhibitors. Synthetic Organic Chemistry, Bioorganic Chemistry & Medicinal Chemistry Post Doctoral Research Scientist Position Available: Email your Resume, Publications (pdf) & Research Experience Research Assistant Position Available Immediately: Complete online application for graduate program, Email your TOEFL& GRE scores, Resume with references, Research interests, & Experience Graduate & Undergraduate Researchers: Email your Resume with references, Research interests and goals. Students interested in Bioorganic, Medicinal & Synthetic Organic Chemistry are strongly encouraged to apply.
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| | Selected Publications |  |
| Journals
Abeywickrama, C.; Matsuda, H .; Jockusch, S.; Zhou, J.; Jang, Y. P.; Chen, Bi-X.; Itagaki, Y.; Turro, N. J.; Erlanger. (2007). "Immunochemical Recognition of A2E, a Pigment in the Lipofuscin of Retinal Pigment Epithelial Cells", Proceedings of the National Academy of sciences, USA, 104, 14610-14615. Download (954 kb PDF).
Abeywickrama, C.; Rotenberg, S. A; Baker, A. D. (2006). "Inhibition of Protein Kinase C by Dequalinium Analogues: Structure-Activity Studies on Head Group Variations", Bioorganic & Medicinal Chemistry, 14, 7796-7803. Download (201 kb PDF).
Abeywickrama, C.; Baker, A. D. (2004). "Efficient Synthesis of 1,4,5,12-Tetraazatriphenylene and Derivatives", Journal of Organic Chemistry, 69, 7741. Download (210 kb PDF).
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