| Dr. Hongjun Wang | |  |
 | | Dr. Hongjun Wang | | Assistant Professor, Biomedical Engineering | | Location: | 416 McLean Hall Building |
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BME/NANO 650:Advanced Biomaterials
Upon completion of this course, students will be able to demonstrate an understanding of the major classes of engineering materials, their principal properties, and design requirements that serve as both the basis for materials selection, as well as for the ongoing development of new materials. This course is substantially differentiated from introductory materials courses by its very specific focus on materials whose use puts them in direct contact with physiological systems. Thus, the course begins with brief sections on inflammatory response, thrombosis, infection, and device failure. It then concentrates on developing the fundamental materials science and engineering concepts underlying the structure-property relationships in both synthetic and natural polymers, metals and alloys, and ceramics relevant to in vivo medical-device technology. |
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BME 675:Nanomedicine
This course will provide a comprehensive introduction to the rapidly developing field of nanomedicine, and discuss the application of nanoscience and nanotechnology in medicine such as in diagnosis, imaging and therapy, surgery and drug delivery. |
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| | School: Schaefer School of Engineering & Science | | Department: Chemistry, Chemical Biology & Biomedical Engineering | Program: Biomedical Engineering
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| | Research & Education | |
| | Research | | Wang's primary research interests focus on tissue engineering, biomaterials design, signal transduction, stem cells, and nanomedicine. Ongoing research activities include multiscale design and growing hierarchical cardiovascular and musculoskeletal tissues, controllable differentiation of stem cells by understanding cellular signal transduction, as well as nanotechnology in targeting delivery and controlled release of bioactive molecules. Postdoctoral Research Associate Position
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| | | Education | - Ph.D. (Biomedical Engineering), University of Twente, the Netherlands, 2003
- Ph.D. (Polymer Chemistry & Physics), Nankai University, China, 1998
- M.S. (Polymer Chemistry & Physics), Nankai University, China, 1995
- B.S. (Chemistry), Nankai University, China, 1992
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| | Experience & Service | |
| | Experience | - Assistant Professor (08/05-present), Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ
- Postdoctoral Research Fellow (08/03-07/05), Department of Dermatology, Harvard Medical School, Boston, MA
- Research Fellow (08/03-07/05), Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA
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| | Achievements & Professional Societies | |
| | Professional Societies | Member, American Society of Engineering Education Member, Tissue Engineering & Regenerative Medicine International Society (TERMIS) Member, Society for Biomaterials |
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| | Selected Publications | |
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C.Erisken, D. M. Kalyon and H. Wang. (2008). "Functionally graded electrospun polycaprolactone and ßtricalcium phosphate nanocomposites for tissue engineering applications", Biomaterials, 29 (30), 4065-4073.
C. Erisken, D. M. Kalyon and H. Wang. (2008). "A hybrid twin screw extrusion/electrospinning method to process nanoparticle‐incorporated electrospun nanofibers", Nanotechnology, 19 (16), 165302.
X. Yang, J. Shah, H. Wang. (2008). "Nanofiber enabled “layer‐by‐layer” approach toward threedimensional tissue formation", Tissue Engineering, (in press).
Y. Guan, L. Ou, H. Wang, Y. Xu, J. Chen, J. Zhang, Y. Yu, D. Kong. (2008). "Tissue engineering of urethra using human VEGF165 gene modified bladder urothelial cells", Artificial Organs, 32 (2), 91.
Xiaochuan Yang, Kentebe R. Ogbolu, Hongjun Wang. (2008). "Multifunctional Nanofibrous Scaffold for Tissue Engineering", Journal of Experimental Nanoscience, 3 (4), 329-345.
Jun Zhang, Hongxu Qi, Hongjun Wang, Ping Hu, Lailiang Ou, Shuhua Guo, Jing Li, Yongzhe Che, Yaoting Yu, Deling Kong. (2006). "Engineering of vascular grafts with genetically modified bone marrow mesenchymal stem cells on Poly (propylene carbonate) graf", Artif Organs. 30 (12), 898-905.
H. Wang, J. Pieper, F. Peters, C.A. Van Blitterswijk and E.N. Lamme. (2005). "Synthetic scaffold morphology controls human dermal connective tissue formation", J Biomed Mater Res A., 74 (4), 523-32.
H.J. Wang, M. Bertrand-De Haas, J. Riesle J, E. Lamme and C.A. Van Blitterswijk. (2003). "Tissue engineering of dermal substitutes based on porous PEGT/PBT copolymer scaffolds: comparison of culture conditions.", J Mater Sci Mater Med., 14 (3), 235-40.
F. Li and H.J. Wang. (1998). "Study on the synthesis of high elongation polyurethane.", European Polymer Journal, 34 (1), 59.
Report
H. Wang and I.E. Kochevar. (2005). "Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes.", Free Radic Biol Med., 38 (7), 890-7.
H. Wang, C.A. Van Blitterswijk, M. Bertrand-De Haas, A.H. Schuurman and E.N. Lamme. (2004). "Improved enzymatic isolation of fibroblasts for the creation of autologous skin substitutes.", In Vitro Cell Dev Biol Anim., 40 (8-9), 268-77.
J. De Boer, H.J. Wang and C.A. Van Blitterswijk. (2004). "Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells.", Tissue Eng., 10 (3-4), 393-401.
H.J. Wang, J. Pieper, R. Schotel, C.A. van Blitterswijk, E.N. Lamme. (2004). "Stimulation of skin repair is dependent on fibroblast source and presence of extracellular matrix.", Tissue Eng., 10 (7-8), 1054-64.
H.J. Wang, M. Bertrand-de Haas, C.A. van Blitterswijk, E.N. Lamme. (2003). "Engineering of a dermal equivalent: seeding and culturing fibroblasts in PEGT/PBT copolymer scaffolds. ", Tissue Eng., 9 (5), 909-17.
J. Ma, H. Wang, B. He and J. Chen. (2001). "A preliminary in vitro study on the fabrication and tissue engineering applications of a novel chitosan bilayer material as a scaffold of human neofetal dermal fibroblasts.", Biomaterials, 22 (4), 331-6.
H.J. Wang, J. Ma, Y. Zhang and B. He. (1997). "Adsorption of bilirubin on the polymeric β-cyclodextrin supported by partially aminated polyacrylamide gel.", Reactive & Functional Polymers, 32 1.
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