Dr. Wang’s implementation of nanotechnology in the field of Tissue Engineering has led to dramatic improvements in this industry, and provides exciting opportunities for future health advances. His research encompasses many areas, and primarily involves the use of biomaterial scaffolds that act as a bridge upon which new cells can grow in the case of patient trauma related to skin, nerves and bone. Dr. Wang is a leading authority in Tissue Engineering, and has determined that by using nanotechnology as a means to improve upon scaffolding and develop a novel “bottom-up” approach, the healing and patient integration process would increase exponentially.
In addition to Tissue Engineering, Dr Wang also researches biomaterials design, signal transduction, stem cells, and nanomedicine. His research activities include multiscale design and growing hierarchical cardiovascular and musculoskeletal tissues, controllable differentiation of stem cells, as well as nanotechnology in targeting delivery and controlled release of bioactive molecules.
Professor Wang is a member of the American Society of Engineering Education, Tissue Engineering & Regenerative Medicine International Society (TERMIS) and the Society for Biomaterials. He is known as a pioneer of the Tissue Engineering field, has contributed to many journal articles and conference proceedings, and recently received a grant from the National Institute of Health (NIH) for his work involving development of skin grafts that promote rapid re-growth due to improved scaffolding on the bone tissue engineering frontier. |
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Xiaochuan Yang, Kentebe R. Ogbolu, Hongjun Wang. (2008). Multifunctional Nanofibrous Scaffold for Tissue Engineering, Journal of Experimental Nanoscience, 3 (4), 329-345
C.Erisken, D. M. Kalyon and H. Wang. (2008). Functionally graded electrospun polycaprolactone and ßtricalcium phosphate nanocomposites for tissue engineering applications, Biomaterials, 29 (30), 4065-4073
X. Yang, J. Shah, H. Wang. (2008). Nanofiber enabled “layer‐by‐layer” approach toward threedimensional tissue formation, Tissue Engineering, (in press)
C. Erisken, D. M. Kalyon and H. Wang. (2008). A hybrid twin screw extrusion/electrospinning method to process nanoparticle‐incorporated electrospun nanofibers, Nanotechnology, 19 (16), 165302
Y. Guan, L. Ou, H. Wang, Y. Xu, J. Chen, J. Zhang, Y. Yu, D. Kong. (2008). Tissue engineering of urethra using human VEGF165 gene modified bladder urothelial cells, Artificial Organs, 32 (2), 91
Jun Zhang, Hongxu Qi, Hongjun Wang, Ping Hu, Lailiang Ou, Shuhua Guo, Jing Li, Yongzhe Che, Yaoting Yu, Deling Kong. (2006). Engineering of vascular grafts with genetically modified bone marrow mesenchymal stem cells on Poly (propylene carbonate) graf, Artif Organs. 30 (12), 898-905
H. Wang, J. Pieper, F. Peters, C.A. Van Blitterswijk and E.N. Lamme. (2005). Synthetic scaffold morphology controls human dermal connective tissue formation, J Biomed Mater Res A., 74 (4), 523-32
H.J. Wang, M. Bertrand-De Haas, J. Riesle J, E. Lamme and C.A. Van Blitterswijk. (2003). Tissue engineering of dermal substitutes based on porous PEGT/PBT copolymer scaffolds: comparison of culture conditions, J Mater Sci Mater Med., 14 (3), 235-40
F. Li and H.J. Wang. (1998). Study on the synthesis of high elongation polyurethane, European Polymer Journal, 34 (1), 59
H. Wang and I.E. Kochevar. (2005). Involvement of UVB-induced reactive oxygen species in TGF-beta biosynthesis and activation in keratinocytes, Free Radic Biol Med., 38 (7), 890-7
H. Wang, C.A. Van Blitterswijk, M. Bertrand-De Haas, A.H. Schuurman and E.N. Lamme. (2004). Improved enzymatic isolation of fibroblasts for the creation of autologous skin substitutes, In Vitro Cell Dev Biol Anim., 40 (8-9), 268-77
J. De Boer, H.J. Wang and C.A. Van Blitterswijk. (2004). Effects of Wnt signaling on proliferation and differentiation of human mesenchymal stem cells, Tissue Eng., 10 (3-4), 393-401
H.J. Wang, J. Pieper, R. Schotel, C.A. van Blitterswijk, E.N. Lamme. (2004). Stimulation of skin repair is dependent on fibroblast source and presence of extracellular matrix, Tissue Eng., 10 (7-8), 1054-64
H.J. Wang, M. Bertrand-de Haas, C.A. van Blitterswijk, E.N. Lamme. (2003). Engineering of a dermal equivalent: seeding and culturing fibroblasts in PEGT/PBT copolymer scaffolds, Tissue Eng., 9 (5), 909-17
J. Ma, H. Wang, B. He and J. Chen. (2001). A preliminary in vitro study on the fabrication and tissue engineering applications of a novel chitosan bilayer material as a scaffold of human neofetal dermal fibroblasts, Biomaterials, 22 (4), 331-6
H.J. Wang, J. Ma, Y. Zhang and B. He. (1997). Adsorption of bilirubin on the polymeric β-cyclodextrin supported by partially aminated polyacrylamide gel, Reactive & Functional Polymers, 32 1
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