Animal Tissue Protocol
Purpose: It is the purpose of this policy to provide ethical, practical, humane, and reasonable methods for the sharing or use of animal tissue(s)/carcass(es) prior to animal carcass disposal. Note, for any tissue(s) to be collected prior to euthanasia, the procedure for tissue harvesting must be included in an IACUC-approved Animal Protocol. If the procedure is not already included in an IACUC-approved Animal Protocol, then an Animal Protocol Amendment Application must be submitted to and receive approval from the IACUC before tissue harvesting can commence.
The tissues to which this policy applies are those:
- Purchased commercially.
- Provided/received from protocol-approved animals prior to animal disposal.
Applicability: This policy applies to all animals and animal tissues used, housed, or maintained for teaching or research purposes at Stevens Institute of Technology (SIT).
This policy does not apply to the transfer of live animals between Animal Protocols. For such transfers, please refer to the Transfer of Animals policy.
Exceptions: Any of the following, if purchased commercially, are exempt from this policy: preserved or purified tissues, histological fixed samples, sera and antibodies.
Adherence to Regulations: SIT will adhere to all animal use laws, rules, regulations, and guidelines including those described in the “9th CFR,” the PHS Policy, the Guide for Care and Use of Laboratory Animals and international, state and local laws. In matters of perceived inconsistencies between this policy and other governing guidelines or statutes, the IACUC will review the issues raised and recommend an appropriate resolution to the SIT Institutional Official, who will serve as the arbitrator.
Administration: The Institutional Animal Care and Use Committee will administer this policy and is responsible for review and revision of this policy.
Tissue: Any part of a vertebrate animal, including tissue, organ and carcass, that contributes to the individual’s or species’ homeostasis when the animal is alive.
To purchase or provide/receive any animal tissue:
- The purchaser/recipient must complete an Animal Tissue Protocol Application. The application must be submitted to and approved by the IACUC prior to tissue purchase or receipt.
If the tissue to be purchased/received will contain radioactive, hazardous, infectious, or recombinant DNA material, the Animal Tissue Protocol Application must also receive approval from the Institutional Bio-Safety Committee prior to tissue purchase or receipt.
- Any Animal Protocol from which any tissue is to be provided must be approved by the IACUC for tissue sharing. The Principal Investigator for the Animal Protocol may request such approval by filing with the IACUC an Animal Protocol Amendment Application. If any aspect of animal treatment (care, use, euthanasia, disposal, etc.) is to be modified to meet the requirements of tissue harvesting, the details and purpose of the modification(s) must be described on the Animal Protocol Amendment Application. If an Animal Protocol Amendment Application is submitted, it must be approved by the IACUC before any tissue may be provided.
Federal Register, Department of Agriculture, Animal and Plant Inspection Service, 9 CFR Parts 1, 2, and 3. Animal Welfare; Proposed Rules. pp. 10821-10954. Government Printing Office, Washington DC, March 15, 1989. Retrieved from: http://awic.nal.usda.gov/final-rules-animal-welfare-9-cfr-parts-1-and-2
Public Health Service Policy on Humane Care and Use of Laboratory Animals: National Institutes of Health, Office of Laboratory Animal Welfare. Public Health Service: Policy on Humane Care and Use of Laboratory Animals (8/7/02). Retrieved from: http://grants.nih.gov/grants/olaw/references/phspol.htm
Protection of Human Subjects, OPRR Reports, Revised 10/16/2008. Retrieved from: http://www.hhs.gov/ohrp/policy/cdebiol.html