Dr. Richard Schlegel received his M.D. and Ph.D. degrees from Northwestern University Medical School, and was a resident and post-doctoral fellow at Harvard Medical School (Brigham Hospital) in the fields of Pathology and Virology. Beginning in 1980, Dr. Schlegel was an investigator, then a senior investigator at the National Cancer Institute (NCI), and later served as chief of the Cell Regulation and Transformation Section in the Laboratory of Tumor Virus Biology at NCI. In 1990, he joined Georgetown University Medical Center as an associate professor in the Department of Pathology, and became department chair in 2003. Dr. Schlegel’s laboratory at Georgetown University developed the human papillomavirus (HPV) vaccine, which was awarded the dominant patent for the vaccine technology from the U.S. Patent Office in 2005, and in June 2006 received approval from the U.S. Food and Drug Administration to use the HPV vaccine in humans. HPV causes almost all incidences of cervical cancer, the second-leading cause of cancer deaths in women worldwide. Based on his work elucidating the mechanism by which HPV causes cancer, Dr. Schlegel has applied the knowledge gained to the field of regenerative medicine and developed a breakthrough technology that enables the conditional reprogramming and growth of primary human cells of epithelial origin in culture. This technology is being applied to drug development and personalized medicine, as cancer biopsies can be grown in the lab to assess which drugs will be most beneficial for a particular patient.
Dr. William B. Rouse received his B.S. from the University of Rhode Island, and his S.M. and Ph.D. from the Massachusetts Institute of Technology. He is currently the Alexander Crombie Humphreys Chair in Economics of Engineering in the School of Systems and Enterprises, Director of the Center for Complex Systems and Enterprises at Stevens Institute of Technology and Professor Emeritus in the School of Industrial and Systems Engineering at the Georgia Institute of Technology. His previous positions at Georgia Institute of Technology include Executive Director of the university- Tennenbaum Institute and Chair of the School of Industrial and Systems Engineering. Dr. Rouse was also the CEO of two innovative software companies – Enterprise Support Systems and Search Technology – and held faculty positions at Georgia Tech, University of Illinois, Delft University of Technology, and Tufts University. His expertise includes individual and organizational decision-making and problem solving, as well as design of organizations and information systems. In these areas, he has consulted with well over one hundred large and small enterprises in the private, public, and non-profit sectors, where he has worked with several thousand executives and senior managers. His current research focuses on understanding and managing complex public-private systems, such as healthcare, energy and defense, with emphasis on mathematical and computational modeling of these systems for the purpose of policy design and analysis. Dr. Rouse has been designated a lifetime National Associate of the National Research Council and National Academies.