Chemistry is often known as the central science, bridging the gap between the life sciences and physical science, and ranging from the very practical to the highly theoretical. It is the science of matter - its structure, its properties, and how it changes.

All around us we see the discoveries of chemistry: synthetic fabrics, aspirin, penicillin and other pharmaceuticals, detergents, better fuels, plastics, and more abundant food. Chemists enjoy the excitement and rewards of discovery and creation.

Career opportunities exist in research (creating new knowledge or synthesizing new chemicals) or in quality control (testing and analysis) in pharmaceuticals, petroleum, polymers and plastics, paints and adhesives, electronic materials, waste treatment, agricultural chemistry, and foods and fragrances, in addition to many other industries. Chemists are employed in hospitals, as well as clinical, environmental control, and criminology laboratories. Chemistry also occupies a pivotal role in the high-technology areas of bioinformatics, biotechnology, materials technology, ceramics, polymers, and electronic materials. The Stevens program prepares you for employment with companies in these industries, and for graduate programs in chemistry or biochemistry.

The program is based on a solid foundation in the major areas of chemistry and biochemistry. Additional courses in advanced chemistry are available in those areas in which Stevens has unique strengths, such as polymer chemistry, natural products, medicinal chemistry, biochemistry, computational chemistry, and instrumental analysis. Research is strongly encouraged due to its importance in preparing for a career in chemistry; it also helps develop independence in solving open-ended problems.

The Stevens chemistry program is certified by the American Chemical Society (ACS).

A minor in chemistry must include the following courses:

• CH 115,
• CH 117 General Chem I + Lab;
• CH 116, CH 118 General Chem II + Lab;
• CH 241 Organic Chemistry I;
• CH 242 Organic Chemistry II;
• CH 421 Chemical Dynamics,
• CH 362 Instrumental Analysis I;
• and either CH 412 Inorganic Chemistry or CH 580 Biochemistry I.

This sequence meets the American Chemical Society guidelines for a minor in chemistry. A further requirement for a minor in Chemistry is that at least two chemistry courses approved by the advisor in the Chemistry and Chemical Biology Department which are not part of the student’s major requirement must be included for a minor.

Chemical biology is the application of exact science, particularly chemistry, to the understanding and utilization of biological phenomena. The scientific approach to understanding living systems ultimately leads to the cell - the basis of all living systems. Modern biology focuses on how cells originate, differentiate, multiply, and function, with emphasis on their molecular components, their chemical and physical properties, and their interaction.

Chemical biology includes genetic engineering, the design and modification of genetic material, and molecular biology. It is an exciting field at the very core of biotechnology. Today's biology laboratory is equipped with sophisticated instrumentation to stimulate muscle tissue and measure action potentials; to determine the size, shape, and electrical charge of protein molecules; and to follow reactions within the cell. Biologists can study biological phenomena under controlled conditions to explore the mechanisms governing growth, differentiation, behavior, evolution, and aging-knowledge that provides a foundation for modern medicine. The field of medicine relies heavily on modern biology.

The Stevens program in chemical biology provides excellent preparation for the student to pursue a career in medicine, and satisfies requirements for admission to professional schools of medicine, dentistry, and veterinary medicine. Our program features the study of cell and molecular biology, molecular genetics, physiology, biochemistry, biophysical chemistry, organic and physical chemistry, and instrumental analysis. Equipped with this rigorous background - and here is where the Stevens chemical biology program differs from traditional biology and pre-medicine programs - our graduates also find employment in industrial research and pathology laboratories. Many continue their studies at the graduate level in the biological sciences, biochemistry, chemistry, or biophysics.

The chemical biology program is certified by the American Chemical Society (ACS) option - biochemistry.

A minor in chemical biology includes at least the following courses:

• CH 115,
• CH 117 General Chemistry I + Lab;
• CH 116, CH 118 General Chemistry II + Lab;
• CH 241 Organic Chemistry I;
• CH 242 Organic Chemistry II;
• CH 421 Chemical Dynamics;
• CH 281 Biology and Biotechnology;
• CH 381 Cell Biology;
• CH 382 Biological Systems;
• CH 580 Biochemistry I;
• and CH 484 Introduction to Molecular Genetics.

A further requirement is that the student's minor program must include two chemical biology courses which are not part of the student's major program.

If you are pursuing the special combined degree program in medicine or dentistry, you are enrolled in the Accelerated Chemical Biology Program. A heavy course load is required during the three years of the program at Stevens, and completion of the B.S. degree requirements relies on transfer credit from the first year of study at the affiliated medical/dental school. Thus, enrolling in the Accelerated Chemical Biology Program is restricted to students admitted to these special programs.

Mission and Objectives

The Stevens biomedical engineering program produces graduates who possess a broad foundation in engineering and liberal arts, combined with a depth of disciplinary knowledge. This knowledge is mandatory for success in a biomedical engineering career. Biomedical engineering is also an enabling step for a career in medicine, dentistry, business, or law.

The objectives of the biomedical engineering program are to prepare students to:

• Obtain employment and succeed in careers with companies and government organizations in the biomedical field, such as those in the areas of implant and device design and manufacturing, biomaterials, medical instrumentation, medical imaging, healthcare, oversight, and research;
• Utilize their broad-based education to define and solve complex problems, particularly those related to design, in the biomedical engineering field and effectively communicate the results;
• Understand and take responsibility for social, ethical, and economic factors related to biomedical engineering and its application;
• Function effectively on and provide leadership to multidisciplinary teams;
• Demonstrate a facility to seek and use knowledge as the foundation for lifelong learning; and

Be prepared for successful advanced study in biomedical engineering or entry to graduate professional programs such as medicine, dentistry, business, or law.

The following are requirements for graduation of all engineering students and are not included for academic credit. They will appear on the student record as pass/fail.

Physical Education

All engineering students must complete a minimum of three semester credits of Physical Education (P.E.). A large number of activities are offered in lifetime, team, and wellness areas. Students must complete at least one course in their first semester at Stevens; the other two can be completed at any time, although it is recommended that this be done within the first half of the students' program of study. Students can enroll in more than the minimum required P.E. for graduation and are encouraged to do so.

Participation in varsity sports can be used to satisfy the full P.E. requirement.

Participation in supervised, competitive club sports can be used to satisfy up to two credits of the P.E. requirement with approval from the P.E. Coordinator.

English Language Proficiency

All students must satisfy an English Language proficiency requirement.

PLEASE NOTE: A comprehensive Communications Program will be implemented for the Class of 2009. This may influence how the English Language Proficiency requirement is met. Details will be added when available.

Huge amounts of data are being generated by the new and powerful techniques for determining the structures of biological molecules and manipulating biomolecular sequences. Bioinformatics makes use of mathematical and computer science techniques to process the information that is pouring out of laboratories so it can be used for further scientific advances. The Stevens Bioinformatics Program is built on the foundations of chemical biology. After the first two years in the Chemical Biology Program, the Bioinformatics student begins replacing certain electives with mathematics and computer science courses, provided that CS 115 is taken in the freshman year.

The third and fourth years of the Bioinformatics concentration are given below:

The extreme complexity - and fragility - of biological molecules has made it necessary to develop special techniques and instrumentation for their detection and analysis. These methods were employed in the Human Genome Project, and have become vital in drug development efforts and in the field called Chemical Ecology. The bioanalytical chemist is a valued scientist in medical and biomedical research and in the pharmaceutical, flavors, and fragrances industries.

The program in Bioanalytical Chemistry is built on the foundations of Chemical Biology. After the first two years in the regular Chemical Biology Program, the Bioanalytical Chemistry student begins concentrating on special techniques such as mass spectrometry, nuclear magnetic resonance, and separations.

The Third and Fourth Years of the program are shown below:

The Accelerated Chemical Biology program gives you the opportunity to earn the B.S. degree at Stevens and the M.D. degree at the University of Medicine and Dentistry of New Jersey (UMDNJ)-New Jersey Medical School, or the D.M.D. degree at UMDNJ-New Jersey Dental School, in a total of seven years.

More information on this program can be found in the pre-professional and Accelerated Programs section of this catalog. You will also find a discussion of a program called Undergraduate Projects in Technology and Medicine (UPTAM), which is available to specially selected Stevens undergraduates.

Graduate study in the chemical sciences offers research opportunities of great variety and scope. It offers, too, an unusual receptivity to different kinds of research interests, from the most immediate and practical to the highly theoretical.

The Department of Chemistry and Chemical Biology includes faculty and programs in chemistry, as well as in the emerging area of chemical biology. In fact, Stevens pioneered this area with the first undergraduate program in Chemical Biology in the late 1970s. Chemists and biologists share instruments and collaborate on joint educational and research programs. The close proximity of these disciplines encourages cooperation and provides access to equipment and expertise not usually available within a single department.

The Master of Science and Doctor of Philosophy degrees are offered in chemistry or chemical biology with concentrations in physical chemistry, organic chemistry, analytical chemistry, polymer chemistry, chemical biology, and bioinformatics. Admission to the graduate program in chemistry requires an undergraduate education in chemistry. Admission to the chemical biology program requires either an undergraduate degree in chemistry with strong biology background or an undergraduate degree in biology with strong chemistry background.

Polymer synthesis and characterization, methods of instrumental analysis, medicinal chemistry, and structural chemistry (theoretical, as well as experimental) are areas of chemistry in which the department has attained international recognition. Research in chemical biology focuses on protein trafficking through membranes, cell signaling pathways involved in cancer and tissue repair, drug encapsulation and dosing, and proteomics.

The department is the home for the Center for Mass Spectrometry - one of the best equipped mass spectrometry laboratories anywhere. Included are Electrospray, MALDI, GC/LC MS, and other new techniques used in pioneering work in chemistry and biology.

The department is housed in a modern building with well-equipped laboratories for tissue-culture work, protein separation and analysis, and small animal studies. State-of-the-art instrumentation is also available, including confocal microscopy, PCR, radio-isotope labeling, fluorometry, double-beam spectrophotometry, Fourier-transform infrared spectroscopy, nuclear magnetic resonance and high performance liquid chromatography, thermal analysis, and electron tunneling microscopy.

Periodically, the department invites a preeminent scientist for a sequence of informal talks and formal lectures. Previous lecturers have included Kenneth Pitzer and Herman Mark, and the Nobelists William Lipscomb, Sir Derek Barton, Ilya Prigogine, Arthur Kornberg, Rosalyn Yalow, Sidney Altman, and George Palade. Periodically, The Stivala Lectures in Chemistry invites an outstanding scientist for a day of lectures and discussions on timely topics in chemistry. Dr. James Cooper, M.D., established this lecture series in memory of his father Charles Cooper, who was a close friend of Professor Salvatore Stivala, a professor of chemistry and chemical engineering at Stevens.

The department believes the vitality of an academic community depends on interaction among its members, and that teaching and learning are essential activities for students and professors alike.

Thirty graduate credits in an approved plan of study, that include the following core courses, are required for the Master of Science degree. Areas of concentration include analytical chemistry, chemical biology, organic chemistry, physical chemistry and polymer chemistry, and others can be designed. Research may be included in master's degree programs, either as a Special Research Problem (CH 800) or a Master's Thesis (CH 900), and is counted towards the 30 credits required for the degree. All fellows and teaching or research assistants are expected to complete a thesis.

Core Courses in Chemistry
    (Prerequisites may be required)

CH 681 Biochemistry II
    CH 687 Molecular Genetics
    CH 690 Cellular Signal Transduction
    One Advanced Chemistry Course (with recommendation of research advisor)

Core Courses in Chemical Biology

    CH 561 Instrumental Methods of Analysis
    CH 580 Biochemistry I
    CH 582 Biophysical Chemistry
    CH 640 Advanced Organic and Heterocyclic Chemistry I
    CH 668 Computational Biology
    CH 687 Molecular Genetics

Additional courses are chosen depending on the student's interests and background. The advisor must approve all elective courses.

Success in the field of medical technologies requires a highly interdisciplinary approach. A symbiotic relationship between these four discrete areas must be struck: clinical, industry, patient, and device. Failure to satisfy the requirements and expectations in any one area could prohibit the acceptance of a product or therapy. Certainly, the best and most elegant solutions will satisfy the requirements and expectations of each of the areas.

The core of the Stevens Biomedical Engineering program is distinguished by its consideration of these areas as an integrated system, each area representing a group of critical components required in order for the system to operate. Many other programs fail to consider all four of these components or fail to integrate them comprehensively.

The Stevens BME M.E. program allows for study in one of three avenues: advanced interdisciplinary biomedical engineering research, advanced training in biomedical engineering for engineers with an undergraduate degree in another discipline, or as a minor concentration for graduate engineers in other disciplines. In addition, the research avenue can lead directly into a Ph.D. program.

Common Requirements for Students with BME/Non-BME Background:

Admission to the doctoral program is based on 1) GRE score and 2) reasonable evidence that the student will prove capable of specialization on a broad intellectual foundation. Specifically, students will be admitted to the doctoral program only if the Admissions Committee feels that he/she is reasonably well-prepared for the Qualifying Examinations in Chemistry or Chemical Biology, which must be passed within a 10-month period after acquiring 30 graduate credits. Applicants with good academic records who lack this level of preparation may be admitted initially to the M.S. program.

A student enrolled in the master’s program in Chemistry or Chemical Biology must request admission to the doctoral program through the department’s Admissions Committee. Continuation in the doctoral program is contingent on passing the Qualifying Examinations, Preliminary Examination, and meeting all other requirements.

Elective Options

The following are typical examples of specialization areas:

Analytical Chemistry
CH 650 Spectra and Structure Determination
CH 660 Advanced Instrumental Analysis
CH 661 Advanced Instrumental Analysis Laboratory
CH 662 Separation Methods in Analytical and Organic Chemistry
CH 666 Modern Mass Spectrometry

Chemical Biology
CH 580 Biochemistry I
CH 678 Experimental Microbiology
CH 681 Biochemistry II – Bio-Molecular Structure and Function
CH 682 Biochemical Laboratory Techniques
CH 684 Molecular Biology Laboratory Techniques
CH 685 Medicinal Chemistry
CH 686 Immunology
CH 688 Methods in Chemical Biology
CH 690 Cellular Signal Transduction
CH 780 Selected Topics in Biochemistry I
CH 782 Selected Topics in Bioorganic Chemistry

Organic Chemistry
CH 640 Advanced Organic and Heterocyclic Chemistry I
CH 641 Advanced Organic and Heterocyclic Chemistry II
CH 642 Synthetic Organic Chemistry
CH 646 Chemistry of Natural Products
CH 650 Spectra and Structure Determination
CH 685 Medicinal Chemistry

Physical Chemistry
CH 620 Chemical Thermodynamics and Kinetics
CH 621 Quantum Chemistry
CH 622 Molecular Spectroscopy
CH 623 Chemical Kinetics
CH 624 Statistical Mechanics
CH 650 Spectra and Structure Determination

Polymer Science
CH 670 Polymer Synthesis
CH 671 Physical Chemistry of Polymers
CH 672 Macromolecules in Modern Technology
CH 674 Polymer Functionality

Other Areas of Specialization
Programs in other areas of specialization, such as Biochemistry, etc., can be designed by including the appropriate courses in that area and completing a research topic in the sub-discipline as approved by the research advisor.

Electives
To complete the course requirements for the degree, a student may choose additional courses with the approval of the advisor. Special courses are frequently offered under the title of Special (or Selected) Topics, which can be included with the permission of the advisor. Some courses are offered as reading courses, with no designated lecture schedule.

Degree Requirements

Research Proposals
All doctoral students in the Department of Chemistry and Chemical Biology must present two written research proposals and defend them in an oral examination.

Language Proficiency
The Department of Chemistry and Chemical Biology no longer requires a foreign language examination for the Ph.D. degree. However, every student is required to possess a high level of proficiency in written and spoken English. International students are required to take an English proficiency examination before beginning graduate course work, and one or more remedial English courses (without credit), if necessary. The Department will not waive this requirement for any student.

Doctoral Dissertation
The policies and regulations governing the doctoral dissertation are described in detail in the Stevens Catalog and the Manual for Graduate Students.   

In addition to the degree programs, the department currently offers seven Graduate Certificate Programs. The courses may be used towards a master’s degree. Each Graduate Certificate Program is a self-contained and highly-focused collection of courses carrying 12 or more graduate credits.

Analytical Chemistry

CH 561 Instrumental Methods of Analysis
CH 660 Advanced Instrumental Analysis
CH 662 Separation Methods in Analytical and Organic Chemistry
CH 666 Modern Mass Spectrometry

Bioinformatics

CH 664 Computer Methods in Chemistry
CH 668 Computational Biology 
CH 681 Biochemistry II
CH 760 Chemoinformatics or CS 580 The Logic of Program Design

Biomedical Chemistry

CH 642 Synthetic Organic Chemistry
CH 646 Chemistry of Natural Products

and two of the following courses (with advisor approval):

CH 647 Chemistry and Pharmacology of Drugs
CH 685 Selected Topics in Medicinal Chemistry
CH 800 Special Research Problems in Chemistry

Biomedical Engineering

BME 506 Biomechanics
BME 505 Biomaterials
BME 504 Medical Instrumentation and Imaging
BME 503 Physiological Systems

Chemical Biology

CH 580 Biochemistry I
CH 681 Biochemistry II
CH 686 Immunology
CH 687 Molecular Genetics

Chemical Physiology

CH 580 Biochemistry I
CH 583 Physiology
CH 684 Molecular Biology Laboratory Techniques

and one of the following courses with the approval of your program advisor:

CH 686 Immunology
CH 690 Cellular Signal Transduction
CH 800 Special Research Problems in Chemistry

Laboratory Methods in Chemical Biology

CH 561 Instrumental Methods of Analysis
CH 682 Biochemical Laboratory Techniques
CH 684 Molecular Biology Laboratory Techniques
CH 689 Cell Biology Laboratory Techniques

Polymer Chemistry

CH 670 Synthetic Polymer Chemistry
CH 671 Physical Chemistry of Polymers
CH 672 Macromolecules in Modern Technology
CH 673 Special Topics in Polymer Chemistry
CH 674 Polymer Functionality

The above Graduate Certificate Programs are regular graduate courses and are part of the Master of Science in Chemistry program.