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 | | Dr. Xiaojun Yu | | Assistant Professor of CBME | | Location: | 426 Burchard Building | | Phone: | 201.216.5256 | | Fax: | 201.216.8306 | | Email: | xyu@stevens.edu |
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BME 602:Principles of Tissue Engineering
This course is an introduction to the field of Tissue Engineering. It is rapidly emerging as a therapeutic approach to treating damaged or diseased tissues in the biotechnology industry. In essence, new and functional living tissue can be fabricated using living cells combined with a scaffolding material to guide tissue development. Such scaffolds can be synthetic, natural, or a combination of both. This course will cover the advances in the field of cell biology, molecular biology, material science, and their relationship towards developing novel ‘tissue engineered’ materials. |
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| | School: Schaefer School of Engineering & Science | | Department: Chemistry, Chemical Biology & Biomedical Engineering | Program: Biomedical Engineering
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| | | Research | | Dr. Yu's primary research interests focus on tissue engineering, polymeric biomaterials and drug delivery.
His current research activities include nano- and micro-scale functionalization of biomimic three-dimensional scaffolds for neural and musculoskeletal tissue repair and regeneration, investigation of cell and material interactions in bioreactors, development of controlled release systems for the delivery of growth factors and drugs, manipulation of microenvironment for stem cell proliferation and differentiation. |
| | | Education | - Ph.D. (Biomedical Engineering), Case Western Reserve University, Cleveland, OH, 01/2002
- M.S. (Biomedical Engineering), Peking Union Medical College), Beijing, China, 11/92
- B.E. (Polymeric Materials and Chemical Engineering), Tsinghua University, Beijing, China. 07/89
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| | | Experience | - Assistant Professor (06/05-present), Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ
- Research Associate (04/03-06/05), Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA
- Research PostDoc Associate (11/01-03/03), Department of Chemical Engineering, Drexel University, Philadelphia, PA
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| | | Professional Societies | | The Society For Biomaterials.
The Materials Research Society.
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| | Journals
X. Yu and R.V. Bellamkonda. (2001). "Dorsal root ganglia neurite extension across mechanical and charged interfaces.", Journal of Neuroscience Research, (66), 303-310.
Y. Zhong, X. Yu, R. Gilbert, R.V. Bellamkonda. (2001). "Stabilizing electrode-host interfaces: a tissue engineering approach.", Journal of Rehabilitation Research and Development, 38 (6), 627-632.
D.A. Eavarone, X. Yu and R.V. Bellamkonda. (2000). "Receptor-mediated targeting of C6 glioma by transferrin-coupled liposomes.", Journal of Biomedical Materials Research, 51 (1), 10-14.
G.P. Dillon, X. Yu and R.V. Bellamkonda. (2000). "The polarity and magnitude of ambient charge influences three-dimensional neurite extension from DRGs", Journal of Biomedical Materials Research, 51 (3), 510-519.
G.P. Dillon, X. Yu, A. Sridharran, J.P. Ranieri and R.V. Bellamkonda. (1998). "The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold.", Journal of Biomaterials Science: Polymer Edition 9, 1015-1114.
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X. Yu, E.A. Botchwey, E.M. Levine, S.R. Pollack and C.T. Laurencin. (2004). "Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotype expression and matrix mineralization", Proc Natl Acad Sci USA. 101 (31), 11203-8.
X. Yu and R.V. Bellamkonda. (2003). "Tissue-engineered scaffolds are effective alternatives to autografts for bridging peripheral nerve gaps. ", Tissue Engineering, 9 (3), 421-430.
N.J. Meilander, X. Yu, N.P. Ziats and R.V. Bellamkonda. (2001). "Lipid-based microtubular drug delivery vehicles.", J Control Release, 71 (1), 141-52.
A.P. Balgude, X. Yu, A. Szymanski and R.V. Bellamkonda. (2001). "Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures.", Biomaterials, 22 (10), 1077 -1084.
X. Yu, G.P. Dillon and R.V. Bellamkonda. (1999). "A laminin and nerve growth factor laden 3D matrix for enhanced neurite extension.", Tissue Engineering, 5 (4), 291-304.
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